Evidence map›Paper›PMID 15374648›Full record

ReviewPeptides2004

A walk-through of the yeast mating pheromone response pathway.

Lee Bardwell

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Peptides, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  9. Article
  10. Article
  11. Article
  12. Review
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  15. Article
  16. Mitotic and pheromone-specific intrinsic polarization cues interfere with gradient sensing inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Lee BardwellDepartment of Developmental and Cell Biology, 2208 Natural Sciences I, University of California, Irvine, CA 92697-2300, USA. bardwell@uci.edu

Funding

MAP KINASE CASCADE SIGNAL TRANSMISSION AND SPECIFICITYR01GM060366 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARDWELL, LEE S · 2000 to 2008
$2.2M
A signal transduction pathway database/modeling systemR33GM069013 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI MJOLSNESS, ERIC D · 2004 to 2006
$1.7M
A signal transduction pathway database/modeling systemR21GM069013 · NIGMS · UNIVERSITY OF CALIFORNIA IRVINE · PI MJOLSNESS, ERIC D · 2003 to 2003
$157k
NIGMS NIH HHS GM60366NIGMS NIH HHS GM69013NIGMS NIH HHS R01 GM060366
6 · The paper itself

Abstract

The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae responds to the presence of peptide mating pheromone in its surroundings is one of the best understood signaling pathways in eukaryotes, yet continues to generate new surprises and insights. In this review, we take a brief walk down the pathway, focusing on how the signal is transmitted from the cell-surface receptor-coupled G protein, via a MAP kinase cascade, to the nucleus.

Indexed as

Genes, FungalCell MembraneGTP-Binding ProteinsHumansMAP Kinase Kinase KinasesMAP Kinase Signaling SystemModels, BiologicalPeptidesPheromonesProtein BindingProtein Structure, TertiarySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionGTP-Binding ProteinsMAP Kinase Kinase KinasesPeptidesPheromonesSaccharomyces cerevisiae ProteinsSte11 protein, S cerevisiae

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.