ArticleGenetics2005
Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice.
Article in Genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed.
- Investigating Motor Coordination Using BXD Recombinant Inbred Mice to Model the Genetic Underpinnings of Developmental Coordination Disorder.Genes, brain, and behavior · 2025Article
- Intra-iliac bone marrow injection as a novel alternative to intra-tibial inoculation in rat model.Stem cell research & therapy · 2021Article
- Article
- Contrasting genetic architectures in different mouse reference populations used for studying complex traits.Genome research · 2015Review
- Anxiety is correlated with running in adolescent female mice undergoing activity-based anorexia.Behavioral neuroscience · 2015Article
- A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder.Frontiers in behavioral neuroscience · 2015Article
- Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy.Mediators of inflammation · 2015Article
- Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes.Frontiers in neuroscience · 2014Article
- A large QTL for fear and anxiety mapped using an F2 cross can be dissected into multiple smaller QTLs.Genes, brain, and behavior · 2013Article
- High-precision genetic mapping of behavioral traits in the diversity outbred mouse population.Genes, brain, and behavior · 2013Article
- Anxiety genetics - findings from cross-species genome-wide approaches.Biology of mood & anxiety disorders · 2013Article
- Forward genetic approaches to understanding complex behaviors.Current topics in behavioral neurosciences · 2012Review
- Genetic contributions to behavioural diversity at the gene-environment interface.Nature reviews. Genetics · 2011Review
- The influence of sex and estrous cycle on QTL for emotionality and ethanol consumption.Mammalian genome : official journal of the International Mammalian Genome Society · 2011Article
- Behavioral and genetic investigations of low exploratory behavior in Il18r1(-/-) mice: we can't always blame it on the targeted gene.Brain, behavior, and immunity · 2010Article
- QTL analysis of measures of mouse home-cage activity using B6/MSM consomic strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2010Article
- Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.PLoS pathogens · 2010Article
- Comparison of three strains of diabetic rats with respect to the rate at which retinopathy and tactile allodynia develop.Molecular vision · 2010Article
- Genetic architecture of voluntary exercise in an advanced intercross line of mice.Physiological genomics · 2010Article
- Quantitative trait locus and haplotype mapping in closely related inbred strains identifies a locus for open field behavior.Mammalian genome : official journal of the International Mammalian Genome Society · 2010Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Anxious behavior in the mouse is a complex quantitative phenotype that varies widely among inbred mouse strains. We examined a panel of chromosome substitution strains bearing individual A/J chromosomes in an otherwise C57BL/6J background in open-field and light-dark transition tests. Our results confirmed previous reports of quantitative trait loci (QTL) on chromosomes 1, 4, and 15 and identified novel loci on chromosomes 6 and 17. The studies were replicated in two separate laboratories. Systematic differences in the overall activity level were found between the two facilities, but the presence of the QTL was confirmed in both laboratories. We also identified specific effects on open-field defecation and center avoidance and distinguished them from overall open-field activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.