Evidence map›Paper›PMID 15368078›Full record

ReviewSpringer seminars in immunopathology2004

Stem-cell transplantation for the treatment of advanced solid tumors.

Yago Nieto, Roy B Jones, Elizabeth J Shpall

Abstract readReview
PubMed Publisher
In one paragraph

Review in Springer seminars in immunopathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Knowledge Levels and Awareness of Stem Cell Donation Among First-Degree Relatives of Patients with Hematological Malignancies.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  3. Article
  4. Article
  5. Stem cells in clinical practice: applications and warnings.Journal of experimental & clinical cancer research : CR · 2011
    Review
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yago NietoUniversity of Colorado Health Sciences Center, 4200 East Ninth Avenue, B-190, Denver, CO 80262, USA. yago.nieto@uchsc.edu
Roy B Jones
Elizabeth J Shpall
The University of Texas MD Anderson Cancer Center · USUniversity of Colorado Health · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Over the past two decades, high-dose chemotherapy (HDC) with autologous stem-cell transplantation (ASCT) has been explored for a variety of solid tumors in adults, particularly breast cancer, ovarian cancer and non-seminomatous germ-cell tumors. The results of prospective phase II studies seemed superior in many cases to the outcome expected with standard-dose chemotherapy (SDC). The value of HDC for adult solid tumors remains, in most instances, a controversial issue, currently under the scrutiny of randomized phase III trial evaluation. ASCT pursuing an immune graft-versus-tumor effect has been evaluated in recent years for patients with advanced and refractory solid malignancies. This article reviews the results of the main phase II and III studies of HDC with ASCT, as well as the preliminary experience using allogeneic transplantation for solid tumors.

Indexed as

Hematopoietic Stem Cell TransplantationAntineoplastic AgentsBone Marrow PurgingBreast NeoplasmsClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicCombined Modality TherapyFemaleGerminomaHumansMaleNeoplasmsOvarian NeoplasmsRandomized Controlled Trials as TopicTransplantation, AutologousTransplantation, HomologousAntineoplastic Agents

Identifiers

PMID15368078
OpenAlexW2062282087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.