ArticleHeart (British Cardiac Society)2004
Patients' perceptions of informed consent in acute myocardial infarction research: a questionnaire based survey of the consent process in the DANAMI-2 trial.
Article in Heart (British Cardiac Society), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Views on consent approaches used in emergency and critical care research: a rapid, systematic review.Trials · 2026Pooled it
- Measuring and evaluating participant understanding of consent processes in clinical trials: a systematic review.Trials · 2026Pooled it
- Participants' understanding of informed consent in clinical trials: A systematic review and updated meta-analysis.PloS one · 2024Pooled it
- How to effectively obtain informed consent in trauma patients: a systematic review.BMC medical ethics · 2019Pooled it
- Pooled it
- Participants' understanding of informed consent in clinical trials over three decades: systematic review and meta-analysis.Bulletin of the World Health Organization · 2015Pooled it
- The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial.Clinical cardiology · 2015Trial
- Patients' experiences of clinical trial participation involving a product remotely assessing study drug adherence.Contemporary clinical trials communications · 2024Article
- Patients acceptance and comprehension to written and verbal consent (PAC-VC).BMC medical ethics · 2023Article
- Determinants of Patient and Surrogate Experiences With Acute Care Research Consent: A Key Informant Interview Study.Journal of the American Heart Association · 2019Article
- Emergency Consent: Patients' and Surrogates' Perspectives on Consent for Clinical Trials in Acute Stroke and Myocardial Infarction.Journal of the American Heart Association · 2019Article
- Understanding preferences regarding consent for pragmatic trials in acute care.Clinical trials (London, England) · 2018Article
- Development and pilot testing of an informed consent video for patients with limb trauma prior to debridement surgery using a modified Delphi technique.BMC medical ethics · 2017Article
- Targeted Consent for Research on Standard of Care Interventions in the Emergency Setting.Critical care medicine · 2017Article
- Confronting Ethical and Regulatory Challenges of Emergency Care Research With Conscious Patients.Annals of emergency medicine · 2016Article
- Understanding motivations to participate in an observational research study: Why do patients enroll?Social work in health care · 2016Article
- Involving patients in enrolment decisions for acute myocardial infarction trials.BMJ (Clinical research ed.) · 2015Article
- Strengths and weaknesses of guideline approaches to safeguard voluntary informed consent of patients within a dependent relationship.BMC medicine · 2014Review
- Accessing health services through the back door: a qualitative interview study investigating reasons why people participate in health research in Canada.BMC medical ethics · 2013Article
- The quality of informed consent: mapping the landscape. A review of empirical data from developing and developed countries.Journal of medical ethics · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyse how patients in the acute phase of a myocardial infarct experience the informed consent procedure of a clinical trial.
designA questionnaire based follow up survey including patients who gave informed consent as well as patients who did not consent to the trial. PATIENTS: 103 patients who gave informed consent and 78 who did not consent to the second Danish acute myocardial infarction trial (DANAMI-2).
results76% of the trial participants and 63% of the non-participants agreed or mostly agreed that they felt able to make a decision about whether or not to participate in the trial; 50% of the trial participants and 34% of the non-participants found it acceptable that patients in their situation have to make such a decision. Only 28% of the trial participants and 7% of the non-participants read the information sheet before they made the decision.
conclusionsInformed consent should be sought in acute myocardial infarction trials despite the emergency situation and the medical condition of the patients. Patients' self assessed ability to make a decision should be explicitly addressed during the informed consent process and patients should not be pressurised into decision making. Physicians and research ethics committees should focus specifically on improving the oral information.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.