Evidence map›Paper›PMID 15365046›Full record

ArticleJournal of clinical microbiology2004

Differing patterns of liver disease progression and hepatitis C virus (HCV) quasispecies evolution in children vertically coinfected with HCV and human immunodeficiency virus type 1.

Sophie Canobio, Cynthia M Guilbert, Myriam Troesch, Johanne Samson, Mireille Lemay, Veronique Anne Pelletier, Anne-Claude Bernard-Bonnin, Rafal Kozielski, Normand Lapointe, Steven R Martin and 1 more

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Vertical transmission of hepatitis C virus: a tale of multiple outcomes.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2013
    Article
  5. Review
  6. Article
  7. Article
  8. The quasispecies nature and biological implications of the hepatitis C virus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sophie CanobioUnité d'immunopathologie virale, Centre de recherche de l'Hôpital Sainte-Justine, 3175 Côte Sainte-Catherine, Room 6735, Montréal (Québec) H3T 1C5, Canada.
Cynthia M Guilbert
Myriam Troesch
Johanne Samson
Mireille Lemay
Veronique Anne Pelletier
Anne-Claude Bernard-Bonnin
Rafal Kozielski
Normand Lapointe
Steven R Martin
Hugo Soudeyns

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) quasispeciation was studied in two children vertically coinfected with HCV and human immunodeficiency virus type 1 (HIV-1). HCV quasispecies diversification and liver injury were more significant in patient C1, who was immunocompetent with anti-HIV therapy, than in patient C2, who was immunosuppressed, in consistency with modulation of HCV quasispeciation and liver injury by immunocompetence in coinfected children.

Indexed as

Infectious Disease Transmission, VerticalAcquired Immunodeficiency SyndromeAntiretroviral Therapy, Highly ActiveChildDisease ProgressionFemaleHepacivirusHepatitis CHumansInfantLiverMaleMolecular Sequence DataPhylogenyPregnancyPregnancy Complications, Infectious

Identifiers

PMID15365046
PMCPMC516277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.