ArticleJournal of clinical microbiology2004
Virulence characteristics and molecular epidemiology of enteroaggregative Escherichia coli isolates from hospitalized diarrheal patients in Kolkata, India.
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 83 citations in OpenAlex.
- Molecular characterization of extended-spectrum β-lactamase (ESBL) and virulent genes in multidrug-resistant Escherichia coli isolated from pharmaceutical and environmental Wastewaters in Dhaka, Bangladesh.Scientific reports · 2026Article
- Are non-lactose-fermentingAccess microbiology · 2023Article
- DiarrhoeagenicAfrican health sciences · 2022Article
- Molecular Epidemiology of EnteroaggregativeInternational journal of molecular sciences · 2020Article
- Comparative analysis of virulence determinants, phylogroups, and antibiotic susceptibility patterns of typical versus atypical Enteroaggregative E. coli in India.PLoS neglected tropical diseases · 2020Article
- Genotypic and phenotypic characterization of enteroaggregativeIranian journal of basic medical sciences · 2020Article
- Article
- Prevalence of Virulence Genes in EnteroaggregativeThe American journal of tropical medicine and hygiene · 2019Article
- Characterization of Diarrheagenic EnteroaggregativeFrontiers in cellular and infection microbiology · 2018Article
- Antibiotic resistance pattern and molecular characterization of extended-spectrum β-lactamase producing enteroaggregativeInfection and drug resistance · 2018Article
- Identification of Subsets of EnteroaggregativeThe American journal of tropical medicine and hygiene · 2017Article
- Molecular Epidemiology of Extended-Spectrum β-Lactamase-ProducingInfectious diseases · 2017Article
- pic gene of enteroaggregative Escherichia coli and its association with diarrhea in Peruvian children.Pathogens and disease · 2016Article
- Microbiological quality of water from the rivers of Curitiba, Paraná State, Brazil, and the susceptibility to antimicrobial drugs and pathogenicity of Escherichia coli.Environmental monitoring and assessment · 2015Article
- Phenotypic and Genotypic Characterization of Enteroaggregative Escherichia coli Strains Isolated From Diarrheic Children in Iran.Jundishapur journal of microbiology · 2015Article
- Adherence and virulence genes of Escherichia coli from children diarrhoea in the Brazilian Amazon.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2015Article
- Occurrence of virulence genes associated with diarrheagenic Escherichia coli isolated from raw cow's milk from two commercial dairy farms in the Eastern Cape Province, South Africa.International journal of environmental research and public health · 2014Article
- Extended spectrum betalactamase producing Enteroaggregative Escherichia coli from young children in Iran.Gastroenterology and hepatology from bed to bench · 2014Article
- Trends in the prevalence of diarrheagenic Escherichia coli among hospitalized diarrheal patients in Kolkata, India.PloS one · 2013Article
- Genotypic and phenotypic characterisation of enteroaggregative Escherichia coli from children in Rio de Janeiro, Brazil.PloS one · 2013Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enteroaggregative Escherichia coli (EAEC) is an important diarrheal enteropathogen defined by aggregative adherence to cultured epithelial cells. We have detected EAEC from 121 (6.6%) of 1,826 hospitalized patients admitted with diarrhea to the Infectious Diseases Hospital in Kolkata, India. Watery diarrhea was recorded significantly (P = 0.0142) more often in children. The majority of the EAEC isolates were not serotypeable (62%) and showed resistance to five or more antibiotics (76%). We studied different virulence genes and the molecular epidemiology of 121 EAEC isolates recovered from diarrheal patients. A PCR assay for detection of virulence genes, an assay for determination of clump formation in liquid culture, and a HeLa cell adherence assay were carried out to characterize the EAEC isolates. Investigations were also conducted to correlate the virulence gene profiles with diarrheal symptoms and molecular epidemiology by pulsed-field gel electrophoresis (PFGE). Two or more virulence genes were detected in 109 (90.1%) EAEC isolates. In the cluster analysis, some isolates with specific gene profiles and phenotypes formed a group or subcluster. This study highlights the comparative distributions of three fimbrial adhesins and other virulence genes among EAEC isolates. The diverse virulence gene and PFGE profiles, along with the existence of diverse serotypes and antibiograms, suggests that the EAEC isolates are genetically heterogeneous in Kolkata.
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