Evidence map›Paper›PMID 15361324›Full record

ReviewCurrent pain and headache reports2004

Post-triptan era for the treatment of acute migraine.

Peter J Goadsby

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Prophylaxis of migraine.Neuropsychiatric disease and treatment · 2006
    Article
  4. Migraine headache: options for acute treatment.Current neurology and neuroscience reports · 2005
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter J GoadsbyInstitute of Neurology, Queen Square, London WC1N 3BG, UK. peterg@ion.ucl.ac.uk
University College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There now is one realized and several attractive targets for the treatment of acute attacks of migraine that will follow and augment the use of serotonin 5-HT1B/1D receptor agonists, the triptans. Calcitonin gene-related peptide (CGRP) receptor blockade recently has been shown to be an effective acute antimigraine strategy; therefore, blockade of CGRP release by inhibition of trigeminal nerves would seem a logical approach. A number of targets are reviewed in this article including serotonin 5-HT1F and 5-HT1D receptors, adenosine A1 receptors, nociceptin, vanilloid TRPV1 receptors, and anandamide CB1 receptors. Development of one or more such compound offers the exciting prospect of new non-vasoconstrictor treatments for migraine and cluster headache.

Indexed as

Acute DiseaseAntidepressive Agents, Second-GenerationCapsaicinCluster HeadacheHumansMigraine DisordersNociceptinOpioid PeptidesReceptor, Adenosine A1Serotonin Receptor AgonistsTrigeminal NerveTryptophanVasodilator AgentsAntidepressive Agents, Second-GenerationCapsaicinNociceptinOpioid PeptidesReceptor, Adenosine A1Serotonin Receptor AgonistsTryptophanVasodilator Agents

Identifiers

PMID15361324
OpenAlexW2030983648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.