Evidence map›Paper›PMID 15356642›Full record

ArticleLeukemia2004

Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites.

B Streubel, I Simonitsch-Klupp, L Müllauer, A Lamprecht, D Huber, R Siebert, M Stolte, F Trautinger, J Lukas, A Püspök and 6 more

Abstract read
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In one paragraph

Article in Leukemia, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 1 pooled it
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 1 synthesis or guideline pooled it, 402 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Observational
  6. Review
  7. Review
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  16. Recent advances in cutaneous lymphoma-implications for current and future classifications.Virchows Archiv : an international journal of pathology · 2023
    Review
  17. Article
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  19. Follicular lymphoma and marginal zone lymphoma: how many diseases?Virchows Archiv : an international journal of pathology · 2023
    Review
  20. Review

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

B StreubelInstitute of Pathology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.
I Simonitsch-Klupp
L Müllauer
A Lamprecht
D Huber
R Siebert
M Stolte
F Trautinger
J Lukas
A Püspök
M Formanek
T Assanasen
H-K Müller-Hermelink
L Cerroni
M Raderer
A Chott
Vienna General Hospital · ATMedical University of Vienna · ATUniversity of Würzburg · DEBayreuth Medical Center · DEMedical University of Graz · ATUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although several recurrent genetic aberrations are known to occur in MALT lymphoma, no comprehensive study on the most prevalent MALT lymphoma-associated genetic aberrations is available. We therefore screened 252 primary MALT lymphomas for translocations t(11;18)(q21;q21), t(14;18)(q32;q21), and t(1;14)(p22;q32), and trisomies 3 and 18. The above-listed translocations occurred mutually exclusively and were detected overall in 13.5, 10.8, and 1.6% of the cases; trisomy 3 and/or 18 occurred in 42.1%. The frequency at which the translocations occurred varied markedly with the primary site of disease. The t(11;18)(q21;q21) was mainly detected in pulmonary and gastric tumors, whereas the t(14;18)(q32;q21) was most commonly found in lesions of the ocular adnexa/orbit, skin, and salivary glands. Trisomies 3 and 18 each occurred most frequently in intestinal and salivary gland MALT lymphomas. Our results demonstrate that the three translocations and trisomies 3 and 18 occur at markedly variable frequencies in MALT lymphoma of different sites.

Indexed as

Chromosome AberrationsGenetic VariationTranslocation, GeneticChromosomes, Human, Pair 11Chromosomes, Human, Pair 14Chromosomes, Human, Pair 18Chromosomes, Human, Pair 3Gene FrequencyHumansIn Situ Hybridization, FluorescenceLymphoma, B-Cell, Marginal ZoneOrgan SpecificityTrisomy

Identifiers

PMID15356642
OpenAlexW2000102591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.