SynthesisBMC family practice2004
Is remission of depressive symptoms in primary care a realistic goal? A meta-analysis.
Synthesis in BMC family practice, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01635218 (Efficacy of Individualized Homeopathic Treatment for Moderate to Severe Depression in Peri- and Postmenopausal Women), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Individualized Homeopathic Treatment for Moderate to Severe Depression in Peri- and Postmenopausal Women: a Randomized Placebo-controlled, Double-blind, Double-dummy, Study Protocol
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of complex system interventions designed to increase recovery from depression in primary care.BMC health services research · 2006Pooled it
- Trial
- A study of a culturally focused psychiatric consultation service for Asian American and Latino American primary care patients with depression.BMC psychiatry · 2011Trial
- Assessment of an enhanced program for depression management in primary care: a cluster randomized controlled trial. The INDI project (Interventions for Depression Improvement).BMC public health · 2007Trial
- Multimodal AI-based systems in major depressive disorder: a review of clinical and translational applications.Frontiers in digital health · 2026Review
- Optimizing and Predicting Antidepressant Efficacy in Patients with Major Depressive Disorder Using Multi-Omics Analysis and the Opade AI Prediction Tools.Brain sciences · 2024Article
- Predictors of Remission in Acute and Continuation Treatment of Depressive Disorders.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021Article
- Low emotion-oriented coping and informal help-seeking behaviour as major predictive factors for improvement in major depression at 5-year follow-up in the adult community.Social psychiatry and psychiatric epidemiology · 2017Article
- Bouncing back: remission from depression in a 12-year panel study of a representative Canadian community sample.Social psychiatry and psychiatric epidemiology · 2014Article
- Geriatric depression in primary care.The Psychiatric clinics of North America · 2011Review
- Homeopathic Individualized Q-Potencies versus Fluoxetine for Moderate to Severe Depression: Double-Blind, Randomized Non-Inferiority Trial.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Depression recovery from the primary care patient's perspective: 'hear it in my voice and see it in my eyes'.Mental health in family medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA primary goal of acute treatment for depression is clinical remission of symptoms. Most meta-analyses of remission rates involve randomized controlled trials (RCTs) using patients from psychiatric settings, but most depressed patients are treated in primary care. The goal of this study was to determine remission rates obtained in RCTs of treatment interventions for Major Depressive Disorder (MDD) conducted in primary care settings.
methodsPotentially relevant studies were identified using computerized and manual search strategies up to May 2003. Criteria for inclusion included published RCTs with a clear definition of remission using established outcome measures.
resultsA total of 13 studies (N = 3202 patients) meeting inclusion criteria were identified. Overall remission rates for active interventions ranged between 50% and 67%, compared to 32% for pill placebo conditions and 35% for usual care conditions.
conclusionsRemission rates in primary care studies of depression are at least as high as for those in psychiatric settings. It is a realistic goal for family physicians to target remission of symptoms as an optimal outcome for treatment of depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.