ArticleImmunogenetics2004
Evolution of MHC-DRB class II polymorphism in the genus Apodemus and a comparison of DRB sequences within the family Muridae (Mammalia: Rodentia).
Article in Immunogenetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- The niche of One Health approaches in Lassa fever surveillance and control.Annals of clinical microbiology and antimicrobials · 2021Review
- Polymorphism of MHC class IIB in an acheilognathid species, Rhodeus sinensis shaped by historical selection and recombination.BMC genetics · 2019Article
- Evidence for selection maintaining MHC diversity in a rodent species despite strong density fluctuations.Immunogenetics · 2016Article
- Maintaining microendemic primate species along an environmental gradient - parasites as drivers for species differentiation.Ecology and evolution · 2014Article
- Genetic variation in the major histocompatibility complex of the European brown hare (Lepus europaeus) across distinct phylogeographic areas.Immunogenetics · 2014Article
- Nonsynonymous substitution rate heterogeneity in the peptide-binding region among different HLA-DRB1 lineages in humans.G3 (Bethesda, Md.) · 2014Article
- Positive selection on MHC class II DRB and DQB genes in the bank vole (Myodes glareolus).Journal of molecular evolution · 2014Article
- Possible influence of B chromosomes on genes included in immune response and parasite burden in Apodemus flavicollis.PloS one · 2014Article
- Domestication does not narrow MHC diversity in Sus scrofa.Immunogenetics · 2013Article
- The functional importance of sequence versus expression variability of MHC alleles in parasite resistance.Genetica · 2012Article
- Independent evolution of functional MHC class II DRB genes in New World bat species.Immunogenetics · 2012Article
- Characterization and evolution of MHC class II B genes in Ardeid birds.Journal of molecular evolution · 2011Article
- Genetic structure and contrasting selection pattern at two major histocompatibility complex genes in wild house mouse populations.Heredity · 2011Article
- Polymorphism and Balancing Selection of MHC Class II DAB Gene in 7 Selective Flounder (Paralichthys olivaceus) Families.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- A 454 multiplex sequencing method for rapid and reliable genotyping of highly polymorphic genes in large-scale studies.BMC genomics · 2010Article
- Characterising functionally important and ecologically meaningful genetic diversity using a candidate gene approach.Genetica · 2010Review
- Polymorphism and signatures of selection in the multimammate rat DQB gene.Immunogenetics · 2010Article
- Validation of internal reference genes for quantitative real-time PCR in a non-model organism, the yellow-necked mouse, Apodemus flavicollis.BMC research notes · 2009Article
- Selection, diversity and evolutionary patterns of the MHC class II DAB in free-ranging Neotropical marsupials.BMC genetics · 2008Article
- Diversifying and purifying selection in the peptide binding region of DRB in mammals.Journal of molecular evolution · 2008Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allelic diversity at major histocompatibility complex (MHC) genes is thought to be maintained by balancing selection over long periods of time, even across multiple speciation events. Trans-species sharing of MHC alleles among genera has been supported by many studies on mammals and fish, but in rodents, the results are ambiguous. We investigated natural levels of MHC- DRB variability and evolutionary processes in the wood mouse (Apodemus sylvaticus) and the yellow-necked mouse (Apodemus flavicollis), which are common, sympatric murid rodents in European forests. Using single-strand conformation polymorphism analysis and DNA sequencing, 38 DRB exon 2 alleles were detected among 162 A. sylvaticus from nine different locations in Germany and Switzerland, and 15 DRB exon 2 alleles were detected among 60 A. flavicollis from three different locations in northern Germany. There was evidence for balancing selection in both species. Phylogenetic analysis, including additional murid taxa, showed that the DRB exon 2 sequences did not separate according to species, consistent with trans-species evolution of the MHC in these taxa.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.