ArticleJournal of materials science. Materials in medicine1999
Elaboration conditions influence physicochemical properties and in vivo bioactivity of macroporous biphasic calcium phosphate ceramics.
Article in Journal of materials science. Materials in medicine, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Development of Bioinspired Biphasic Calcium Phosphate Inks for Manufacturing Bone Scaffolds by Robocasting.3D printing and additive manufacturing · 2024Article
- Histological and Radiological Features of a Four-Phase Injectable Synthetic Bone Graft in Guided Bone Regeneration: A Case Report.International journal of environmental research and public health · 2020Article
- Particulated, Extracted Human Teeth Characterization by SEM⁻EDX Evaluation as a Biomaterial for Socket Preservation: An in vitro Study.Materials (Basel, Switzerland) · 2019Article
- Bioactivity of Biphasic Calcium Phosphate Granules, the Control of a Needle-Like Apatite Layer Formation for Further Medical Device Developments.Frontiers in bioengineering and biotechnology · 2019Article
- Bone regeneration using composite non-demineralized xenogenic dentin with beta-tricalcium phosphate in experimental alveolar cleft repair in a rabbit model.Journal of translational medicine · 2017Article
- Preparation, characterization, and in vitro cytotoxicity evaluation of a novel anti-tuberculosis reconstruction implant.PloS one · 2014Article
- Biphasic calcium phosphate bioceramics for orthopaedic reconstructions: clinical outcomes.International journal of biomaterials · 2011Article
- Indirect rapid prototyping of biphasic calcium phosphate scaffolds as bone substitutes: influence of phase composition, macroporosity and pore geometry on mechanical properties.Journal of materials science. Materials in medicine · 2010Article
- Preparation and characterization of biphasic calcium phosphate ceramics of desired composition.Journal of materials science. Materials in medicine · 2008Article
- Biphasic calcium phosphate in periapical surgery.Journal of conservative dentistry : JCD · 2008Article
- Surface potential and osteoblast attraction to calcium phosphate compounds is affected by selected alkaline hydrolysis processing.Journal of materials science. Materials in medicine · 2004Article
- Biphasic calcium phosphate bioceramics: preparation, properties and applications.Journal of materials science. Materials in medicine · 2003Article
- Testing bone substitutes in a small animal model of revision arthroplasty.Journal of materials science. Materials in medicine · 2002Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two different preparations of biphasic calcium phosphate (BCP) were characterized in vitro: BCP1 from a mechanical mixture of hydroxyapatite (HA) and beta-tricalcium phosphate (beta-TCP) powders, and BCP2 from calcination of a calcium-deficient apatite (CDA). The structural, physicochemical and mechanical parameters of these two preparations were investigated, and two different macroporous BCP1 (MBCP1) and BCP2 MBCP2) implants were manufactured and implanted in rabbit bone for in vivo bioactivity studies. Scanning electron microscopy observations showed that MBCP1 implants had a significantly higher degradation rate (P<0.0001) than MBCP2 implants. This was probably caused by the presence of calcium oxide impurities in BCP1 and the more intimate mixture and stable ultrastructure of BCP2. No significant difference about the newly formed bone rate in these two BCP preparations was observed. Very slight variations in sintering conditions appeared to influence the biodegradation behavior of the two MBCP implants despite their identical HA/-TCP ratios and similar porosity. Precise and complete in vitro characterization enabled us to understand and predict in vivo degradation behavior.
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Registered trials
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