ArticlePlant physiology2004
The Elm1 (ZmHy2) gene of maize encodes a phytochromobilin synthase.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Evolutionary insights into bilin biosynthesis: Functional characterization of pre-PcyA enzymes.Protein science : a publication of the Protein Society · 2026Article
- ZmDof08, a zinc finger transcription factor, plays critical roles in photosynthesis in maize.Plant cell reports · 2025Article
- Loss of phytochromobilin synthase activity leads to larger seeds with higher protein content in soybean.BMC plant biology · 2025Article
- A large deletion conferring pale green leaves of maize.BMC plant biology · 2023Article
- Phytochromes mediate germination inhibition under red, far-red, and white light in Aethionema arabicum.Plant physiology · 2023Article
- Soybean GmHY2a encodes a phytochromobilin synthase that regulates internode length and flowering time.Journal of experimental botany · 2022Article
- Genomic insights into historical improvement of heterotic groups during modern hybrid maize breeding.Nature plants · 2022Article
- A mutation in CsHY2 encoding a phytochromobilin (PΦB) synthase leads to an elongated hypocotyl 1(elh1) phenotype in cucumber (Cucumis sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Identification and fine mapping of a recessive gene controlling zebra leaf phenotype in maize.Molecular breeding : new strategies in plant improvement · 2021Article
- Variation in Maize Chlorophyll Biosynthesis Alters Plant Architecture.Plant physiology · 2020Article
- FLOWERING LOCUS T3 Controls Spikelet Initiation But Not Floral Development.Plant physiology · 2018Article
- Genome-Wide Association Mapping and Genomic Prediction Analyses Reveal the Genetic Architecture of Grain Yield and Flowering Time Under Drought and Heat Stress Conditions in Maize.Frontiers in plant science · 2018Article
- The phycocyanobilin chromophore of streptophyte algal phytochromes is synthesized by HY2.The New phytologist · 2017Article
- Heme oxygenase 1 defects lead to reduced chlorophyll in Brassica napus.Plant molecular biology · 2017Article
- Article
- Chlorophyll deficiency in the maize elongated mesocotyl2 mutant is caused by a defective heme oxygenase and delaying grana stacking.PloS one · 2013Article
- A gene regulatory network model for floral transition of the shoot apex in maize and its dynamic modeling.PloS one · 2012Article
- Physiological and genetic characterization of end-of-day far-red light response in maize seedlings.Plant physiology · 2010Article
- Article
- A multi-treatment experimental system to examine photosynthetic differentiation in the maize leaf.BMC genomics · 2007Article
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8 authors.
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Abstract
The light insensitive maize (Zea mays) mutant elongated mesocotyl1 (elm1) has previously been shown to be deficient in the synthesis of the phytochrome chromophore 3E-phytochromobilin (PPhiB). To identify the Elm1 gene, a maize homolog of the Arabidopsis PPhiB synthase gene AtHY2 was isolated and designated ZmHy2. ZmHy2 encodes a 297-amino acid protein of 34 kD that is 50% identical to AtHY2. ZmHY2 was predicted to be plastid localized and was targeted to chloroplasts following transient expression in tobacco (Nicotiana plumbaginifolia) leaves. Molecular mapping indicated that ZmHy2 is a single copy gene in maize that is genetically linked to the Elm1 locus. Sequence analysis revealed that the ZmHy2 gene of elm1 mutants contains a single G to A transition at the 3' splice junction of intron III resulting in missplicing and premature translational termination. However, flexibility in the splicing machinery allowed a small pool of in-frame ZmHy2 transcripts to accumulate in elm1 plants. In addition, multiple ZmHy2 transcript forms accumulated in both wild-type and elm1 mutant plants. ZmHy2 splice variants were expressed in Escherichia coli and products examined for activity using a coupled apophytochrome assembly assay. Only full-length ZmHY2 (as defined by homology to AtHY2) was found to exhibit PPhiB synthase activity. Thus, the elm1 mutant of maize is deficient in phytochrome response due to a lesion in a gene encoding phytochromobilin synthase that severely compromises the PPhiB pool.
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