Evidence map›Paper›PMID 15347426›Full record

Trial reportBMC health services research2004

Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to change.

Atle Fretheim, Andrew D Oxman, Signe Flottorp

Abstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Pooled it
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  4. Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2015
    Pooled it
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  11. A guide to the Canadian Medical Association handbook on clinical practice guidelines.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2007
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Atle FretheimInformed Choice Research Department, Norwegian Health Services Research Centre, P,O, Box 7004, St, Olavs plass, Oslo, Norway. atle.fretheim@nhsrc.no
Andrew D Oxman
Signe Flottorp

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe a simple approach we used to identify barriers and tailor an intervention to improve pharmacological management of hypertension and hypercholesterolaemia. We also report the results of a post hoc exercise and survey we carried out to evaluate our approach for identifying barriers and tailoring interventions.

methodsWe used structured reflection, searched for other relevant trials, surveyed general practitioners and talked with physicians during pilot testing of the intervention. The post hoc exercise was carried out as focus groups of international researchers in the field of quality improvement in health care. The post hoc survey was done by telephone interviews with physicians allocated to the experimental group of a randomised trial of our multifaceted intervention.

resultsA wide range of barriers was identified and several interventions were suggested through structured reflection. The survey led to some adjustments. Studying other trials and pilot testing did not lead to changes in the design of the intervention. Neither the post hoc focus groups nor the post hoc survey revealed important barriers or interventions that we had not considered or included in our tailored intervention.

conclusionsA simple approach to identifying barriers to change appears to have been adequate and efficient. However, we do not know for certain what we would have gained by using more comprehensive methods and we do not know whether the resulting intervention would have been more effective if we had used other methods. The effectiveness of our multifaceted intervention is under evaluation in a randomised controlled trial.

Indexed as

Guideline AdherenceAnticholesteremic AgentsAntihypertensive AgentsBenzothiadiazinesDiureticsDrug UtilizationEducation, Medical, ContinuingFamily PracticeHumansHypercholesterolemiaHypertensionPractice Guidelines as TopicPractice Patterns, Physicians'Primary Health CareRisk AssessmentSodium Chloride Symporter InhibitorsAnticholesteremic AgentsAntihypertensive AgentsBenzothiadiazinesDiureticsSodium Chloride Symporter Inhibitors

Identifiers

PMID15347426
PMCPMC517506

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.