ArticleApplied and environmental microbiology2004
Degradation of estrogens by Rhodococcus zopfii and Rhodococcus equi isolates from activated sludge in wastewater treatment plants.
Article in Applied and environmental microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Catabolic Mechanism of 17β-Estradiol inJournal of microbiology and biotechnology · 2026Article
- Characterization of a rapid 17β-estradiol-degrading strain, Microbacterium proteolyticum ZJSU01.Applied microbiology and biotechnology · 2025Article
- Diversity of estrogen biodegradation pathways and application in environmental bioremediation.Frontiers in microbiology · 2025Review
- Estradiol metabolism by gut microbiota in women's depression pathogenesis: inspiration from nature.Frontiers in psychiatry · 2025Review
- Nature based solutions for removal of steroid estrogens in wastewater.Frontiers in microbiology · 2024Review
- Identification of essential β-oxidation genes and corresponding metabolites for oestrogen degradation by actinobacteria.Microbial biotechnology · 2022Article
- Review
- Mechanistic and phylogenetic insights into actinobacteria-mediated oestrogen biodegradation in urban estuarine sediments.Microbial biotechnology · 2021Article
- Estrogen induces shift in abundances of specific groups of the coral microbiome.Scientific reports · 2021Article
- Article
- Microbial degradation of steroid sex hormones: implications for environmental and ecological studies.Microbial biotechnology · 2020Review
- Estrone degrading enzymes ofBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- Article
- The Analysis of Estrogen-Degrading and Functional Metabolism Genes inInternational journal of genomics · 2020Article
- LP-UV-Nano MgOMaterials (Basel, Switzerland) · 2019Article
- Changes in microbial communities during the removal of natural and synthetic glucocorticoids in three types of river-based aquifer media.Environmental science and pollution research international · 2019Article
- Testosterone Degradative Pathway ofGenes · 2019Article
- Review
- Features of diclofenac biodegradation by Rhodococcus ruber IEGM 346.Scientific reports · 2019Article
- Isolation and characterization of an estrogen-degrading3 Biotech · 2019Article
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Authors and funding
10 authors.
Funding
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Abstract
We have isolated four strains of Rhodococcus which specifically degrade estrogens by using enrichment culture of activated sludge from wastewater treatment plants. Strain Y 50158, identified as Rhodococcus zopfii, completely and rapidly degraded 100 mg of 17beta-estradiol, estrone, estriol, and ethinyl estradiol/liter, as demonstrated by thin-layer chromatography and gas chromatography-mass spectrometry analyses. Strains Y 50155, Y 50156, and Y 50157, identified as Rhodococcus equi, showed degradation activities comparable with that of Y 50158. Using the random amplified polymorphism DNA fingerprinting test, these three strains were confirmed to have been derived from different sources. R. zopfii Y 50158, which showed the highest activity among these four strains, revealed that the strain selectively degraded 17beta-estradiol during jar fermentation, even when glucose was used as a readily utilizable carbon source in the culture medium. Measurement of estrogenic activities with human breast cancer-derived MVLN cells showed that these four strains each degraded 100 mg of 17beta-estradiol/liter to 1/100 of the specific activity level after 24 h. It is thus suggested that these strains degrade 17beta-estradiol into substances without estrogenic activity.
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