ArticleGenetics2004
Stochastic and epigenetic changes of gene expression in Arabidopsis polyploids.
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
145 citing papers in PubMed.
- Homoeologous exchange-associated ABA catabolism rewiring contributes to salinity tolerance in a synthetic tetraploid rice.Plant cell reports · 2026Article
- Convergence and divergence of DNA methylation and gene expression patterns in neopolyploid Arabidopsis kamchatica.Nature communications · 2026Article
- Empowering plant epigenetics to breed resilience of crops: From nucleolar dominance to transgenerational epigenetic inheritance.The plant genome · 2025Review
- Rapid reprogramming and stabilization of homoeolog expression bias in hexaploid wheat biparental populations.Genome biology · 2025Article
- Differential Gene Expression and Unbalanced Homeolog Expression Bias in 4 Million-Year-Old Allopolyploids of Nicotiana Section Repandae.Genome biology and evolution · 2025Article
- Testing the potential of zebularine to induce heritable changes in crop growth and development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Regulatory networks of coresident subgenomes during rapid fiber cell elongation in upland cotton.Plant communications · 2024Article
- Transgenerational epigenetic inheritance during plant evolution and breeding.Trends in plant science · 2024Review
- Autopolyploids of Arabidopsis thaliana are more phenotypically plastic than their diploid progenitors.Annals of botany · 2023Article
- Moderate DNA methylation changes associated with nitrogen remobilization and leaf senescence in Arabidopsis.Journal of experimental botany · 2022Article
- Epimutations and mutations, nurturing phenotypic diversity.Genetica · 2022Review
- Alkaline Stress Induces Different Physiological, Hormonal and Gene Expression Responses in Diploid and Autotetraploid Rice.International journal of molecular sciences · 2022Article
- Genomic and Meiotic Changes Accompanying Polyploidization.Plants (Basel, Switzerland) · 2022Review
- Concerted genomic and epigenomic changes accompany stabilization of Arabidopsis allopolyploids.Nature ecology & evolution · 2021Article
- ARPEGGIO: Automated Reproducible Polyploid EpiGenetic GuIdance workflOw.BMC genomics · 2021Article
- Polyploidy-associated paramutation in Arabidopsis is determined by small RNAs, temperature, and allele structure.PLoS genetics · 2021Article
- Gene and Transposable Element Expression Evolution Following Recent and Past Polyploidy Events inFrontiers in genetics · 2021Article
- What is quantitative plant biology?Quantitative plant biology · 2021Review
- Article
- The effects of hybridization and genome doubling in plant evolution via allopolyploidy.Molecular biology reports · 2020Review
85 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Polyploidization is an abrupt speciation mechanism for eukaryotes and is especially common in plants. However, little is known about patterns and mechanisms of gene regulation during early stages of polyploid formation. Here we analyzed differential expression patterns of the progenitors' genes among successive selfing generations and independent lineages. The synthetic Arabidopsis allotetraploid lines were produced by a genetic cross between A. thaliana and A. arenosa autotetraploids. We found that some progenitors' genes are differentially expressed in early generations, whereas other genes are silenced in late generations or among different siblings within a selfing generation, suggesting that the silencing of progenitors' genes is rapidly and/or stochastically established. Moreover, a subset of genes is affected in autotetraploid and multiple independent allotetraploid lines and in A. suecica, a natural allotetraploid derived from A. thaliana and A. arenosa, indicating locus-specific susceptibility to ploidy-dependent gene regulation. The role of DNA methylation in silencing progenitors' genes is tested in DNA-hypomethylation transgenic lines of A. suecica using RNA interference (RNAi). Two silenced genes are reactivated in both ddm1- and met1-RNAi lines, consistent with the demethylation of centromeric repeats and gene-specific regions in the genome. A rapid and stochastic process of differential gene expression is reinforced by epigenetic regulation during polyploid formation and evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.