ArticleGenetics2004
Mapping of multiple quantitative trait loci affecting bovine spongiform encephalopathy.
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 4 citations in OpenAlex.
- Taurine and Indicine Haplotype Representation in Advanced Generation Individuals From Three American Breeds.Frontiers in genetics · 2021Article
- Genome-wide association study of infectious bovine keratoconjunctivitis in Angus cattle.BMC genetics · 2013Article
- Association mapping of genetic risk factors for chronic wasting disease in wild deer.Evolutionary applications · 2013Article
- Functional genomics approach for identification of molecular processes underlying neurodegenerative disorders in prion diseases.Current genomics · 2012Article
- PRNP and SPRN genes polymorphism in atypical bovine spongiform encephalopathy cases diagnosed in Polish cattle.Journal of applied genetics · 2012Article
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- Quantitative trait loci associated with the immune response to a bovine respiratory syncytial virus vaccine.PloS one · 2012Article
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- Genomic scan for quantitative trait loci of chemical and physical body composition and deposition on pig chromosome X including the pseudoautosomal region of males.Genetics, selection, evolution : GSE · 2009Article
- Identification of new quantitative trait Loci (other than the PRNP gene) modulating the scrapie incubation period in sheep.Genetics · 2008Article
- A critical analysis of disease-associated DNA polymorphisms in the genes of cattle, goat, sheep, and pig.Mammalian genome : official journal of the International Mammalian Genome Society · 2008Review
- Major quantitative trait loci affect resistance to infectious pancreatic necrosis in Atlantic salmon (Salmo salar).Genetics · 2008Article
- PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle.BMC genetics · 2007Article
- Opinion of the Scientific Panel on biological hazards (BIOHAZ) on the Breeding programme for TSE resistance in sheep.EFSA journal. European Food Safety Authority · 2006Article
- DNA polymorphisms of the prion doppel gene region in four different German cattle breeds and cows tested positive for bovine spongiform encephalopathy.Mammalian genome : official journal of the International Mammalian Genome Society · 2005Article
- Genomewide scan for anal atresia in swine identifies linkage and association with a chromosome region on Sus scrofa chromosome 1.Genetics · 2005Article
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Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A whole-genome scan was conducted to map quantitative trait loci (QTL) for BSE resistance or susceptibility. Cows from four half-sib families were included and 173 microsatellite markers were used to construct a 2835-cM (Kosambi) linkage map covering 29 autosomes and the pseudoautosomal region of the sex chromosome. Interval mapping by linear regression was applied and extended to a multiple-QTL analysis approach that used identified QTL on other chromosomes as cofactors to increase mapping power. In the multiple-QTL analysis, two genome-wide significant QTL (BTA17 and X/Y(ps)) and four genome-wide suggestive QTL (BTA1, 6, 13, and 19) were revealed. The QTL identified here using linkage analysis do not overlap with regions previously identified using TDT analysis. One factor that may explain the disparity between the results is that a more extensive data set was used in the present study. Furthermore, methodological differences between TDT and linkage analyses may affect the power of these approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.