ArticleMolecular and cellular biology2004
The Swi/Snf chromatin remodeling complex is required for ribosomal DNA and telomeric silencing in Saccharomyces cerevisiae.
Article in Molecular and cellular biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- CRISPRi screen highlights chromatin regulation to be involved in formic acid tolerance inEngineering microbiology · 2023Article
- Generation of Remosomes by the SWI/SNF Chromatin Remodeler Family.Scientific reports · 2019Article
- RNA Sequencing Reveals Specific TranscriptomicSignatures Distinguishing Effects of the [Genes · 2019Article
- SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells.Genome research · 2016Article
- The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.Cold Spring Harbor perspectives in medicine · 2016Review
- Ribosome quality control is a central protection mechanism for yeast exposed to deoxynivalenol and trichothecin.BMC genomics · 2016Article
- DAMPs, ageing, and cancer: The 'DAMP Hypothesis'.Ageing research reviews · 2015Review
- Direct interactions promote eviction of the Sir3 heterochromatin protein by the SWI/SNF chromatin remodeling enzyme.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle.PLoS genetics · 2014Article
- Inactivation of chromatin remodeling factors sensitizes cells to selective cytotoxic stress.Biologics : targets & therapy · 2014Article
- Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- The SWI/SNF chromatin remodeling complex influences transcription by RNA polymerase I in Saccharomyces cerevisiae.PloS one · 2013Article
- Linking DNA replication to heterochromatin silencing and epigenetic inheritance.Acta biochimica et biophysica Sinica · 2012Review
- Roles of chromatin remodeling factors in the formation and maintenance of heterochromatin structure.The Journal of biological chemistry · 2011Article
- The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae.Aging · 2011Review
- SWI/SNF and Asf1 independently promote derepression of the DNA damage response genes under conditions of replication stress.PloS one · 2011Article
- Article
- Distinct subregions of Swi1 manifest striking differences in prion transmission and SWI/SNF function.Molecular and cellular biology · 2010Article
- A major role for the Plasmodium falciparum ApiAP2 protein PfSIP2 in chromosome end biology.PLoS pathogens · 2010Article
- Article
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2 authors.
Funding
Abstract
The Swi/Snf chromatin remodeling complex has been previously demonstrated to be required for transcriptional activation and repression of a subset of genes in Saccharomyces cerevisiae. In this work we demonstrate that Swi/Snf is also required for repression of RNA polymerase II-dependent transcription in the ribosomal DNA (rDNA) locus (rDNA silencing). This repression appears to be independent of both Sir2 and Set1, two factors known to be required for rDNA silencing. In contrast to many other rDNA silencing mutants that have elevated levels of rDNA recombination, snf2Delta mutants have a significantly decreased level of rDNA recombination. Additional studies have demonstrated that Swi/Snf is also required for silencing of genes near telomeres while having no detectable effect on silencing of HML or HMR.
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