Evidence map›Paper›PMID 15339201›Full record

ReviewPaediatric drugs2004

Allergic rhinitis in children : diagnosis and management strategies.

William E Berger

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Paediatric drugs, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05348148 (Camillian Saint Mary's Hospital Luodong), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05348148 narecruitingnot on this mapstarted 2020, after this paper: background citation

Camillian Saint Mary's Hospital Luodong

TypeinterventionalSponsorCamillians Saint Mary's Hospital LuodongRan2020 to 2032Enrolled450ConditionsAllergic Rhinitis, Vasomotor RhinitisArmsOral Levocetirizine, Combined Intranasal Mometasone Furoate with oral Levocetirizine, Combined Intranasal Mometasone Furoate with oral Levocetirizine plus intranasal Oxymetazoline
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Efficacy and safety of oral treatments for allergic rhinitis in children: A network meta-analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Role of Allergy in Eustachian Tube Dysfunction.Current allergy and asthma reports · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Atypical "allergic crease".Journal of dermatological case reports · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

William E BergerDepartment of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA. weberger@uci.edu
University of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of allergic rhinitis has been increasing for the last few decades, in keeping with the rising incidence of atopy worldwide. Allergic rhinitis has a prevalence of up to 40% in children, although it frequently goes unrecognized and untreated. This can have enormous negative consequences, particularly in children, since it is associated with numerous complications and comorbidities that have a significant health impact on quality of life. In fact, allergic rhinitis is considered to be a risk factor for asthma. There are numerous signs of allergic rhinitis, particularly in children, that can alert an observant clinician to its presence. Children with severe allergic rhinitis often have facial manifestations of itching and obstructed breathing, including a gaping mouth, chapped lips, evidence of sleep deprivation, a long face, dental malloclusions, and the allergic shiner, allergic salute, or allergic crease. The medical history is extremely important as it can reveal information regarding a family history of atopy and the progression of atopy in the child. It is also important to identify the specific triggers of allergic rhinitis, because one of the keys to successful management is the avoidance of triggers. A tripartite treatment strategy that embraces environmental control, immunotherapy, and pharmacologic treatment is the most comprehensive approach. Immunotherapy has come to be viewed as potentially prophylactic, capable of altering the course of allergic rhinitis. The most recent guidelines for the management of allergic rhinitis issued by the WHO recommend a tiered approach that integrates diagnosis and treatment, in which allergic rhinitis is subclassified both by frequency, as either intermittent or persistent, and by severity, as either mild or moderate to severe. Oral or topical antihistamines and intranasal corticosteroids are the mainstay of pharmacologic therapy for allergic rhinitis, depending upon its severity, and several agents have been approved for use in children aged 5 years old and younger.

Indexed as

Rhinitis, Allergic, PerennialAdolescentAdrenal Cortex HormonesChildChild, PreschoolHistamine H1 AntagonistsHumansIncidencePrevalenceAdrenal Cortex HormonesHistamine H1 Antagonists

Identifiers

PMID15339201
OpenAlexW232013779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.