ReviewJournal of molecular histology2004
Integrin signalling and the cellular response to ionizing radiation.
Review in Journal of molecular histology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- New specific molecular targets for radio-chemotherapy of rectal cancer.Molecular oncology · 2010Trial
- Radiation-induced rhinosinusitis: Mechanism research and clinical progress review.World journal of otorhinolaryngology - head and neck surgery · 2024Review
- Role of Radiation Therapy in Modulation of the Tumor Stroma and Microenvironment.Frontiers in immunology · 2019Review
- The changing paradigm of tumour response to irradiation.The British journal of radiology · 2017Review
- Gene expression response of mice after a single dose of 137CS as an internal emitter.Radiation research · 2014Article
- αν and β1 Integrins mediate Aβ-induced neurotoxicity in hippocampal neurons via the FAK signaling pathway.PloS one · 2014Article
- Characterization of the stem cell niche and its importance in radiobiological response.Seminars in radiation oncology · 2013Review
- 17-β-Estradiol counteracts the effects of high frequency electromagnetic fields on trophoblastic connexins and integrins.Oxidative medicine and cellular longevity · 2013Article
- RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β₃ expression.International journal of nanomedicine · 2012Article
- Metastasis Update: Human Prostate Carcinoma Invasion via Tubulogenesis.Prostate cancer · 2011Article
- Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi.Journal of neuropathology and experimental neurology · 2010Article
- Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease.Biochimica et biophysica acta · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell survival and cycling in mammalian cells are both greatly affected by ionizing radiation and are both strictly controlled by integrated integrin-mediated adhesion to extracellular matrix (ECM) proteins and by binding of growth factors to their cognate receptors. Recent emerging findings show a diverse panel of integrin-dependent signals that are channelled into the regulation and modification of the cellular response to ionizing radiation. Cell adhesion-mediated radioresistance and alteration of DNA damage-induced cell cycle arrest in cells attached to the ECM can be linked to focal adhesion protein signalling. This review summarizes the latest radiobiological and radiooncological findings about integrins and their signal transduction pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.