ArticlePlant physiology2004
Arabidopsis Cys2/His2-type zinc-finger proteins function as transcription repressors under drought, cold, and high-salinity stress conditions.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 256 papers.
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256 citing papers in PubMed, 666 citations in OpenAlex.
- The ZAT7-OTU11-DOA9-CYS13 module enhances salt resistance by suppressing NPF2.4-mediated chloride transport in Arabidopsis.Plant communications · 2026Article
- Apple ZAT11, a C2H2-type zinc finger protein, enhances resistance to Penicillium expansum by affecting jasmonic acid biosynthesis in apple.The New phytologist · 2026Article
- The Structure, Classification, Functional Diversity and Regulatory Mechanism of Plant C2H2 Transcription Factors.Biology · 2026Review
- MsWIP3 functions as a transcriptional regulator affecting alfalfa (Medicago sativa) response under saline -alkali stress.Plant cell reports · 2026Article
- GhZAT11 triggers wound-activated bud growth by accelerating sugar transport and cell division.Nature plants · 2026Article
- Article
- Superabsorbent polymers seed coatings modulate transcriptomic and physiological responses to drought in rapeseed.Frontiers in plant science · 2026Article
- C2H2 Zinc-Finger Transcription Factors Coordinate Hormone-Stress Crosstalk to Shape Expression Bias of the Flavonoid Pathway in Safflower (Current issues in molecular biology · 2025Article
- Functional characterization of four soybean C2H2 zinc-finger genes inPlant signaling & behavior · 2025Article
- The ZAT14 family promotes cell death and regulates expansins to affect xylem formation and salt tolerance in Arabidopsis.The Plant cell · 2025Article
- A pangenome of maize provides genetic insights into drought resistance.Nature genetics · 2025Article
- Functional Analysis of Zinc Finger Protein Transcription FactorPlants (Basel, Switzerland) · 2025Article
- Divide and survive: PuZFP1 coordinates dual root developmental pathways for drought adaptation in Populus.Plant physiology · 2025Article
- Transcriptional gene network involved in drought stress response: application for crop breeding in the context of climate change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Genome-Wide Identification and Functional Analysis ofInternational journal of molecular sciences · 2025Article
- In Silico Characterization and Determination of Gene Expression Levels Under Saline Stress Conditions in the Zinc Finger Family of the C1-2i Subclass inInternational journal of molecular sciences · 2025Article
- A wild-allele GsPP2C-51-a1 enhances tolerance to drought stress in soybean and Arabidopsis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- A novel C2H2-type zinc-finger transcription factor, CitZAT4, regulates ethylene-induced orange coloration in Satsuma mandarin flavedo (Citrus unshiu Marc.).Journal of integrative plant biology · 2025Article
- Identification and functional analyses of drought stress resistance genes by transcriptomics of the Mongolian grassland plant Chloris virgata.BMC plant biology · 2025Article
- The molecular framework balancing growth and defense in response to plant elicitor peptide-induced signals in Arabidopsis.The Plant cell · 2024Article
196 more citing papers are in PubMed but not listed here.
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7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
ZPT2-related proteins that have two canonical Cys-2/His-2-type zinc-finger motifs in their molecules are members of a family of plant transcription factors. To characterize the role of this type of protein, we analyzed the function of Arabidopsis L. Heynh. genes encoding four different ZPT2-related proteins (AZF1, AZF2, AZF3, and STZ). Gel-shift analysis showed that the AZFs and STZ bind to A(G/C)T repeats within an EP2 sequence, known as a target sequence of some petunia (Petunia hybrida) ZPT2 proteins. Transient expression analysis using synthetic green fluorescent protein fusion genes indicated that the AZFs and STZ are preferentially localized to the nucleus. These four ZPT2-related proteins were shown to act as transcriptional repressors that down-regulate the transactivation activity of other transcription factors. RNA gel-blot analysis showed that expression of AZF2 and STZ was strongly induced by dehydration, high-salt and cold stresses, and abscisic acid treatment. Histochemical analysis of beta-glucuronidase activities driven by the AZF2 or STZ promoters revealed that both genes are induced in leaves rather than roots of rosette plants by the stresses. Transgenic Arabidopsis overexpressing STZ showed growth retardation and tolerance to drought stress. These results suggest that AZF2 and STZ function as transcriptional repressors to increase stress tolerance following growth retardation.
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