ReviewJournal of clinical pathology2004
The detection of circulating breast cancer cells in blood.
Review in Journal of clinical pathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- CD44-downregulation in multiple myeloma inhibits cytoskeleton rearrangement through actin depolymerization.Clinical and experimental medicine · 2025Article
- Detection, significance and potential utility of circulating tumor cells in clinical practice in breast cancer (Review).Oncology letters · 2025Review
- Efficacy of Emu Oil Transfersomes for Local Transdermal Delivery of 4-OH Tamoxifen in the Treatment of Breast Cancer.Pharmaceutics · 2020Article
- Remodelling of the bone marrow microenvironment by stromal hyaluronan modulates the malignancy of breast cancer cells.Cell communication and signaling : CCS · 2020Article
- CYP19A1 gene expression in the peripheral blood of Brazilian women with breast cancer relapse.BMC cancer · 2020Article
- Comparative Study of Blood, Tissue and Serum Levels of Carcinoembryonic Antigen (CEA) Detection in Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2019Article
- Single cell analysis of cancer cells using an improved RT-MLPA method has potential for cancer diagnosis and monitoring.Scientific reports · 2015Article
- Molecular markers in peripheral blood of Iranian women with breast cancer.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2013Article
- Photoacoustic Imaging for Cancer Detection and Staging.Current molecular imaging · 2013Article
- Bone metastasis: mechanisms and therapeutic opportunities.Nature reviews. Endocrinology · 2011Review
- Optical Photoacoustic Detection of Circulating Melanoma Cells In Vitro.International journal of thermophysics · 2010Article
- Small breast epithelial mucin (SBEM) has the potential to be a marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer.Clinical & experimental metastasis · 2010Article
- Flow cytometric analysis of CK19 expression in the peripheral blood of breast carcinoma patients: relevance for circulating tumor cell detection.Journal of experimental & clinical cancer research : CR · 2009Article
- CYP17 gene polymorphism and its association with high-risk north Indian breast cancer patients.Journal of human genetics · 2007Article
- Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer.BMC cancer · 2006Article
- Specific detection of cytokeratin 20-positive cells in blood of colorectal and breast cancer patients by a high sensitivity real-time reverse transcriptase-polymerase chain reaction method.The Journal of molecular diagnostics : JMD · 2006Article
- Detection of Survivin-expressing circulating cancer cells in the peripheral blood of breast cancer patients by a RT-PCR ELISA.Clinical & experimental metastasis · 2006Article
- Screening and identification of differentially expressed transcripts in circulating cells of prostate cancer patients using suppression subtractive hybridization.Molecular cancer · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At present, sampling of the lymph nodes or bone marrow for the detection of regions of metastatic disease in patients with breast cancer can only be undertaken at the time of initial diagnosis and surgery. However, the sampling of these tissues and the methods used are inaccurate, time consuming, and cannot be used for easy routine screening to determine disease recurrence and response to treatment. Because of the problems encountered with current methods and tissues sampled at the time of breast cancer diagnosis, this review discusses the urgent requirement for and potential development of a quick, simple, and accurate diagnostic test utilising the haematogenous system, a source of circulating tumour cells in patients with breast cancer, and highly sensitive molecular biological techniques, such as reverse transcription polymerase chain reaction. In addition, this review also highlights potential problems that may be encountered and should be avoided when devising such a test.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.