Evidence map›Paper›PMID 15331509›Full record

ArticleClinical chemistry2004

ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome.

Rossa W K Chiu, Nelson L S Tang, David S C Hui, Grace T Y Chung, Stephen S C Chim, K C Allen Chan, Ying-man Sung, Louis Y S Chan, Yu-kwan Tong, Wing-shan Lee and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Clinical chemistry, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04426253 (Identification of Genetic Factors Determining Disease Course and Preparation of Pharmacogenetic Applications in the New Type of Coronavirus Infection, COVID-19), which is not on this map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04426253 unknown statusnot on this mapstarted 2020, after this paper: background citation

Identification of Genetic Factors Determining Disease Course and Preparation of Pharmacogenetic Applications in the New Type of Coronavirus Infection, COVID-19

TypeobservationalSponsorSzeged UniversityRan2020 to 2021Enrolled1,000ConditionsCOVID-19, Sars-CoV2
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Genetic polymorphisms as multi-biomarkers in severe acute respiratory syndrome (SARS) by coronavirus infection: A systematic review of candidate gene association studies.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Transmembrane protease serine 2 (Life science alliance · 2022
    Article
  6. The role of angiotensin-converting enzyme 2 (The Egyptian journal of medical human genetics · 2022
    Review
  7. The association ofEXCLI journal · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Epigenetic alterations and genetic variations of angiotensin-converting enzyme 2 (ACE2) as a functional receptor for SARS-CoV-2: potential clinical implications.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Review
  12. ACE I/D polymorphism in Czech first-wave SARS-CoV-2-positive survivors.Clinica chimica acta; international journal of clinical chemistry · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Coronavirus: Pure Infectious Disease or Genetic Predisposition.Advances in experimental medicine and biology · 2021
    Article
  20. Host variations in SARS-CoV-2 infection.Turkish journal of biology = Turk biyoloji dergisi · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rossa W K ChiuThe Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin.
Nelson L S Tang
David S C Hui
Grace T Y Chung
Stephen S C Chim
K C Allen Chan
Ying-man Sung
Louis Y S Chan
Yu-kwan Tong
Wing-shan Lee
Paul K S Chan
Y M Dennis Lo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllelesAngiotensin-Converting Enzyme 2CarboxypeptidasesCase-Control StudiesDNAFemaleGenetic Predisposition to DiseaseGenotypeHumansMalePeptidyl-Dipeptidase APolymerase Chain ReactionPolymorphism, Single NucleotideSequence AlignmentSequence Analysis, DNASevere Acute Respiratory SyndromeACE2 protein, humanAngiotensin-Converting Enzyme 2CarboxypeptidasesDNAPeptidyl-Dipeptidase A

Identifiers

PMID15331509
PMCPMC7108155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.