ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
Input-driven components of spike-frequency adaptation can be unmasked in vivo.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- In Vitro Patch-Clamp.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Auditory DUM neurons in a bush-cricket: inhibited inhibitors.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Article
- Temporal processing properties of auditory DUM neurons in a bush-cricket.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
- Neural adaptation accounts for the dynamic resizing of peripersonal space: evidence from a psychophysical-computational approach.Journal of neurophysiology · 2018Article
- Adaptive responses of peripheral lateral line nerve fibres to sinusoidal wave stimuli.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Article
- Response recovery in the locust auditory pathway.Journal of neurophysiology · 2016Article
- Dynamic dendritic compartmentalization underlies stimulus-specific adaptation in an insect neuron.Journal of neurophysiology · 2015Article
- Computational themes of peripheral processing in the auditory pathway of insects.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Review
- Coding space-time stimulus dynamics in auditory brain maps.Frontiers in physiology · 2014Review
- Channel noise from both slow adaptation currents and fast currents is required to explain spike-response variability in a sensory neuron.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Is the rapid adaptation paradigm too rapid? Implications for face and object processing.NeuroImage · 2012Article
- The iso-response method: measuring neuronal stimulus integration with closed-loop experiments.Frontiers in neural circuits · 2012Article
- Neuronal correlates of a preference for leading signals in the synchronizing bushcricket Mecopoda elongata (Orthoptera, Tettigoniidae).The Journal of experimental biology · 2011Article
- Neural adaptation facilitates oscillatory responses to static inputs in a recurrent network of ON and OFF cells.Journal of computational neuroscience · 2011Article
- Reliable detection of predator cues in afferent spike trains of a katydid under high background noise levels.The Journal of experimental biology · 2010Article
- Calcium-dependent control of temporal processing in an auditory interneuron: a computational analysis.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2010Article
- GABAergic signaling increases through the postnatal development to provide the potent inhibitory capability for the maturing demands of the prefrontal cortex.Cellular and molecular neurobiology · 2010Article
- The origin of adaptation in the auditory pathway of locusts is specific to cell type and function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Characterizing the dynamic frequency structure of fast oscillations in the rodent hippocampus.Frontiers in integrative neuroscience · 2009Article
- Influence of sound pressure level on the processing of amplitude modulations by auditory neurons of the locust.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2008Article
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2 authors.
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Abstract
Spike-frequency adaptation affects the response characteristics of many sensory neurons, and different biophysical processes contribute to this phenomenon. Many cellular mechanisms underlying adaptation are triggered by the spike output of the neuron in a feedback manner (e.g., specific potassium currents that are primarily activated by the spiking activity). In contrast, other components of adaptation may be caused by, in a feedforward way, the sensory or synaptic input, which the neuron receives. Examples include viscoelasticity of mechanoreceptors, transducer adaptation in hair cells, and short-term synaptic depression. For a functional characterization of spike-frequency adaptation, it is essential to understand the dependence of adaptation on the input and output of the neuron. Here, we demonstrate how an input-driven component of adaptation can be uncovered in vivo from recordings of spike trains in an insect auditory receptor neuron, even if the total adaptation is dominated by output-driven components. Our method is based on the identification of different inputs that yield the same output and sudden switches between these inputs. In particular, we determined for different sound frequencies those intensities that are required to yield a predefined steady-state firing rate of the neuron. We then found that switching between these sound frequencies causes transient deviations of the firing rate. These firing-rate deflections are evidence of input-driven adaptation and can be used to quantify how this adaptation component affects the neural activity. Based on previous knowledge of the processes in auditory transduction, we conclude that for the investigated auditory receptor neurons, this adaptation phenomenon is of mechanical origin.
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