Evidence map›Paper›PMID 15329383›Full record

ArticleNucleic acids research2004

Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments.

Torstein Tengs, Thomas LaFramboise, Robert B Den, David N Hayes, Jianhua Zhang, Saikat DebRoy, Robert C Gentleman, Keith O'Neill, Bruce Birren, Matthew Meyerson

Abstract readEvaluation Study
In one paragraph

Article in Nucleic acids research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Torstein TengsDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Thomas LaFramboise
Robert B Den
David N Hayes
Jianhua Zhang
Saikat DebRoy
Robert C Gentleman
Keith O'Neill
Bruce Birren
Matthew Meyerson

Funding

BIOSTATISTICS/EPIDEMIOLOGY TRAINING GRANTS IN AIDST32AI007358 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Michael David Hughes · 1989 to 2026
$12.4M
Cancer Virus Discovery by Computational SubtractionR01CA098185 · NCI · DANA-FARBER CANCER INSTITUTE · PI MEYERSON, MATTHEW L · 2003 to 2005
$979k
NCI NIH HHS 1R01CA098185-01A1NCI NIH HHS R01 CA098185NIAID NIH HHS T32 AI007358NIAID NIH HHS T32-AI-07358
6 · The paper itself

Abstract

We have developed a method for genomic representation using Type IIB restriction endonucleases. Representation by concatenation of restriction digests, or RECORD, is an approach to sample the fragments generated by cleavage with these enzymes. Here, we show that the RECORD libraries may be used for digital karyotyping and for pathogen identification by computational subtraction.

Indexed as

BacteriaComputational BiologyComputer SimulationDeoxyribonucleases, Type II Site-SpecificDNA, ConcatenatedGenome, HumanGenomic LibraryGenomicsHumansKaryotypingMarkov ChainsPolymerase Chain ReactionVirusesDeoxyribonucleases, Type II Site-SpecificDNA, Concatenated

Identifiers

PMID15329383
PMCPMC516078

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.