Evidence map›Paper›PMID 1532399›Full record

ArticleJournal of clinical microbiology1992

Phenotypic profile and functional characteristics of human gamma and delta T cells during acute toxoplasmosis.

P De Paoli, G Basaglia, D Gennari, M Crovatto, M L Modolo, G Santini

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. The Armadillo (Frontiers in immunology · 2018
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  9. Human V delta 2+ gamma delta T-cell tolerance to foreign antigens of Toxoplasma gondii.Proceedings of the National Academy of Sciences of the United States of America · 1996
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

P De PaoliDepartment of Microbiology and Immunology, General Hospital USL11, Pordenone, Italy.
G Basaglia
D Gennari
M Crovatto
M L Modolo
G Santini
Azienda Ospedaliera Santa Maria Degli Angeli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gamma and delta (gamma delta) T-cell receptor lymphocytes are increased during acute toxoplasmosis. These cells are BB3+ CD45RO+ CD8-. Purified gamma delta T cells failed to proliferate in response to Toxoplasma gondii antigen (stimulation index, 1.4 +/- 0.6) but were responsive to phytohemagglutinin stimulation (stimulation index, 20.8 +/- 1.9). Natural-killer-like cytotoxicity was strongly acquired only after in vitro culture of purified gamma delta T cells with recombinant interleukin 2 (40% +/- 7% specific lysis). Our data show that gamma delta T-cell receptor T cells with a peculiar phenotype are increased during human acute T. gondii infection.

Indexed as

Receptors, Antigen, T-Cell, gamma-deltaAcute DiseaseAdultAnimalsAntigens, ProtozoanFemaleHumansIn Vitro TechniquesLymphocyte ActivationMalePhenotypeT-Lymphocyte SubsetsToxoplasmaToxoplasmosisAntigens, ProtozoanReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID1532399
PMCPMC265143
OpenAlexW1894531754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.