ReviewRheumatology international2005
New developments in ochronosis: review of the literature.
Review in Rheumatology international, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 122 citations in OpenAlex.
- Total Knee Arthroplasty in Alkaptonuric Patient With Ochronotic Arthropathy.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Case Report: Ochronotic arthropathy mimicking spondyloarthritis: a case-based review of diagnostic pitfalls and a novel likely pathogenic HGD variant.Frontiers in genetics · 2026Article
- Alkaptonuria with Fracture Neck of Femur - A Case Report.Journal of orthopaedic case reports · 2024Article
- Black Bone Disease: Ochronotic Arthritis Detected during Knee Arthroplasty.Journal of bone metabolism · 2023Article
- Rare Case of Ochronosis with Fracture of Intracapsular Neck of Femur and Scoliosis: A Case Report.Journal of orthopaedic case reports · 2023Article
- Descemet's membrane folds in ochronosis: a case report.Journal of medical case reports · 2022Article
- Total Knee Replacement in Alkaptonuric Ochronosis.Acta bio-medica : Atenei Parmensis · 2022Article
- Total knee arthroplasty and physical therapy for arthropathy in alkaptonuria: A 4-year follow-up case report.Frontiers in surgery · 2022Article
- Perioral and gingival hyperpigmentation secondary to cultural tattooing.International journal of women's dermatology · 2021Article
- Intraoperative Diagnosis of a Rare Case of Arthropathy - A Case Report and Review of Literature.Journal of orthopaedic case reports · 2020Article
- Assessment of Thyroid Function in Patients With Alkaptonuria.JAMA network open · 2020Article
- Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups.Arthroplasty (London, England) · 2019Article
- Ochronotic arthritis and ochronotic Achilles tendon rupture in alkaptonuria: A 6 years follow-up case report in China.Medicine · 2019Article
- Serum Oxidative-Antioxidative Status in Patients With Alkaptonuria.Journal of clinical medicine research · 2019Article
- Knee Arthroscopy: A Diagnostic and Therapeutic Tool for Management of Ochronotic Arthropathy.Arthroscopy techniques · 2018Article
- Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy.Acta orthopaedica et traumatologica turcica · 2016Article
- An Unusual Case of Facial Hyperpigmentation Solved on Histopathology.Journal of clinical and diagnostic research : JCDR · 2016Article
- Ochronosis of the knee with secondary osteoarthritis requiring total knee replacement in a patient with cryptogenic organising pneumonia.BMJ case reports · 2016Article
- Ochronotic arthropathy as a paradigm of metabolically induced degenerative joint disease. A case-based review.Clinical rheumatology · 2016Review
- The Distribution of Ochronosis in Osteoarthritic Articular Cartilage in a Knee.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ochronosis commonly affects all connective tissue. Recognition of changes secondary to the deposition of ochronotic pigments has increased with advances in diagnostic technology, allowing both improved imaging and early biochemical and genetics-based diagnosis of alkaptonuria, the cause of ochronosis. Successful symptomatic treatment of ochronotic arthropathy with joint replacement has been documented, and a new pharmacotherapeutic agent, nitisinone, is currently under investigation for both prevention and treatment of ochronosis. This review of the literature highlights recently recognized complications, new diagnostic techniques, and treatment options.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.