ArticleInfection and immunity2004
Chemokine gene expression in toll-like receptor-competent and -deficient mice infected with Leishmania major.
Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- Blockade of TLR2 and TLR4 Attenuates Inflammatory Response and Parasite Load in Cutaneous Leishmaniasis.Frontiers in immunology · 2021Article
- Pathogen Evasion of Chemokine Response Through Suppression of CXCL10.Frontiers in cellular and infection microbiology · 2019Article
- Histological and immunological differences between zoonotic cutaneous leishmaniasis due to Leishmania major and sporadic cutaneous leishmaniasis due to Leishmania infantum.Parasite (Paris, France) · 2019Article
- Article
- Cytokine Effect of TLR3, TLR4, and TLR7 Agonists Alone or Associated withBioMed research international · 2018Article
- Protective role of 5-lipoxigenase during Leishmania infantum infection is associated with Th17 subset.BioMed research international · 2014Article
- Deception and manipulation: the arms of leishmania, a successful parasite.Frontiers in immunology · 2014Review
- Immunotherapy and Immunochemotherapy in Visceral Leishmaniasis: Promising Treatments for this Neglected Disease.Frontiers in immunology · 2014Review
- Host cell signalling and leishmania mechanisms of evasion.Journal of tropical medicine · 2012Article
- Toll-like receptors in leishmania infections: guardians or promoters?Journal of parasitology research · 2012Article
- Role of chemokines in regulation of immunity against leishmaniasis.Experimental parasitology · 2010Review
- Human immunodeficiency virus and leishmaniasis.Journal of global infectious diseases · 2010Article
- Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2010Article
- Keratinocytes determine Th1 immunity during early experimental leishmaniasis.PLoS pathogens · 2010Article
- Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice.PLoS pathogens · 2010Article
- Toll-like receptors and leishmaniasis.Infection and immunity · 2008Review
- Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site.The Journal of clinical investigation · 2008Article
- CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence.The Journal of experimental medicine · 2006Article
- Interaction of Bartonella henselae with endothelial cells promotes monocyte/macrophage chemoattractant protein 1 gene expression and protein production and triggers monocyte migration.Infection and immunity · 2005Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
We studied the expression of a subset of chemokines, including RANTES/CCL5, MIP-1alpha/CCL3, IP-10/CXCL10, and MCP-1/CCL2, in Toll-like receptor (TLR)-competent and -deficient mice after infection with Leishmania major. Chemokine expression at the site of infection (the footpad), in the draining lymph nodes and in the spleens of infected animals was determined by using two different methods of analysis. The results indicate that L. major infection causes overall upregulation of RANTES/CCL5, MIP-1alpha/CCL3, IP-10/CXCL10, and MCP-1/CCL2 in the footpads and lymph nodes, while expression of these chemokines is constitutive in the spleens of TLR4-competent mice (C57BL/10ScSn) and TLR4-deficient mice (C57BL10/ScN). Different patterns of expression were detected depending on the time postinfection, but there was little variation in the expression of these four chemokines in the presence or absence of TLR4.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.