Evidence map›Paper›PMID 15319229›Full record

ReviewAnnals of botany2004

The effect of stress on genome regulation and structure.

Andreas Madlung, Luca Comai

Open access · bronzeAbstract readReview
In one paragraph

Review in Annals of botany, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 1 synthesis or guideline pooled it, 307 citations in OpenAlex.

  1. Pooled it
  2. Adaptation to Climatic Change and Epigenetic Modifications of Soil Microbiome.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. mScience advances · 2023
    Article
  10. Article
  11. Article
  12. Use ofHeliyon · 2023
    Article
  13. Epigenetic Changes Occurring in Plant Inbreeding.International journal of molecular sciences · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Methylome changes inFrontiers in plant science · 2023
    Article
  18. Article
  19. Article
  20. Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andreas MadlungUniversity of Puget Sound, Department of Biology, Tacoma, WA 98416, USA.
Luca Comai
University of Puget Sound · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStresses exert evolutionary pressures on all organisms, which have developed sophisticated responses to cope and survive. These responses involve cellular physiology, gene regulation and genome remodelling. SCOPE: In this review, the effects of stress on genomes and the connected responses are considered. Recent developments in our understanding of epigenetic genome regulation, including the role of RNA interference (RNAi), suggest a function for this in stress initiation and response. We review our knowledge of how different stresses, tissue culture, pathogen attack, abiotic stress, and hybridization, affect genomes. Using allopolyploid hybridization as an example, we examine mechanisms that may mediate genomic responses, focusing on RNAi-mediated perturbations.

conclusionsA common response to stresses may be the relaxation of epigenetic regulation, leading to activation of suppressed sequences and secondary effects as regulatory systems attempt to re-establish genomic order.

Indexed as

Evolution, MolecularGenome, PlantClimateDNA, PlantGene SilencingPlant DiseasesPlantsPolyploidyRNA, PlantTranscription, GeneticDNA, PlantRNA, Plant

Identifiers

PMID15319229
PMCPMC4242226
OpenAlexW2111659126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.