Evidence map›Paper›PMID 15317805›Full record

ArticleJournal of bacteriology2004

Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures.

Rie Sugai, Hisayo Shimizu, Ken-Ichi Nishiyama, Hajime Tokuda

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Suppressors ofInternational journal of molecular sciences · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rie SugaiInstitute of Molecular and Cellular Biosciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.
Hisayo Shimizu
Ken-Ichi Nishiyama
Hajime Tokuda
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GnsA overproduction was previously found to suppress both the secG null mutation and the fabA6 mutation in Escherichia coli by increasing the unsaturated fatty acid contents. We report here that it also increased the acidic phospholipid contents at 20 degrees C but not at 37 degrees C. GnsA overproduction at 20 degrees C specifically inhibited phosphatidylethanolamine synthesis and therefore caused the increase in the proportion of acidic phospholipids.

Indexed as

Genes, BacterialEscherichia coliEscherichia coli ProteinsFatty Acids, UnsaturatedFatty Acid Synthase, Type IIHydro-LyasesMembrane ProteinsPhosphatidylethanolaminesPhospholipidsSEC Translocation ChannelsTemperature3-hydroxyacyl-(acyl-carrier-protein) dehydrataseEscherichia coli ProteinsFatty Acids, UnsaturatedFatty Acid Synthase, Type IIGnsA protein, E coliHydro-LyasesMembrane ProteinsphosphatidylethanolaminePhosphatidylethanolaminesPhospholipidsSecG protein, E coliSEC Translocation Channels

Identifiers

PMID15317805
PMCPMC516848
OpenAlexW2013329467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.