ArticleThe Plant cell2004
NAPP and PIRP encode subunits of a putative wave regulatory protein complex involved in plant cell morphogenesis.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 90 citations in OpenAlex.
- Recent insights into the plant ARP2/3 complex.Protoplasma · 2026Review
- Independent roles of Arp2/3 complex and RIC4 protein in the control of epidermal cell shape.Planta · 2026Article
- Tuning the rheostat of immune gene translation.Stress biology · 2023Article
- Comparative Transcriptomic Analysis Revealed the Suppression and Alternative Splicing of Kiwifruit (International journal of molecular sciences · 2023Article
- Plant HEM1 specifies a condensation domain to control immune gene translation.Nature plants · 2023Article
- The ARP2/3 complex, acting cooperatively with Class I formins, modulates penetration resistance in Arabidopsis against powdery mildew invasion.The Plant cell · 2021Article
- The Imaging of Guard Cells ofCells · 2021Article
- Kinase Partner Protein Plays a Key Role in Controlling the Speed and Shape of Pollen Tube Growth in Tomato.Plant physiology · 2020Article
- GmNAP1 is essential for trichome and leaf epidermal cell development in soybean.Plant molecular biology · 2020Article
- Arp2/3 Complex Is Required for Auxin-Driven Cell Expansion Through Regulation of Auxin Transporter Homeostasis.Frontiers in plant science · 2020Article
- A Nck-associated protein 1-like protein affects drought sensitivity by its involvement in leaf epidermal development and stomatal closure in rice.The Plant journal : for cell and molecular biology · 2019Article
- Molecular cloning of the tomato Hairless gene implicates actin dynamics in trichome-mediated defense and mechanical properties of stem tissue.Journal of experimental botany · 2016Article
- Homologs of SCAR/WAVE complex components are required for epidermal cell morphogenesis in rice.Journal of experimental botany · 2016Article
- Allyl Isothiocyanate Inhibits Actin-Dependent Intracellular Transport in Arabidopsis thaliana.International journal of molecular sciences · 2015Article
- Differential Growth in Periclinal and Anticlinal Walls during Lobe Formation in Arabidopsis Cotyledon Pavement Cells.The Plant cell · 2015Article
- The Arabidopsis CURVY1 (CVY1) gene encoding a novel receptor-like protein kinase regulates cell morphogenesis, flowering time and seed production.BMC plant biology · 2014Article
- Root hairs.The arabidopsis book · 2014Article
- Plant cell shape: modulators and measurements.Frontiers in plant science · 2013Review
- The endoplasmic reticulum is a reservoir for WAVE/SCAR regulatory complex signaling in the Arabidopsis leaf.Plant physiology · 2013Article
- ARP2/3 localization in Arabidopsis leaf pavement cells: a diversity of intracellular pools and cytoskeletal interactions.Frontiers in plant science · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ARP2/3 complex is an important regulator of actin nucleation and branching in eukaryotic organisms. All seven subunits of the ARP2/3 complex have been identified in Arabidopsis thaliana, and mutation of at least three of the subunits results in defects in epidermal cell expansion, including distorted trichomes. However, the mechanisms regulating the activity of the ARP2/3 complex in plants are largely unknown. In mammalian cells, WAVE and WASP proteins are involved in activation of the ARP2/3 complex. WAVE1 activity is regulated by a protein complex containing NAP1/HEM/KETTE/GEX-3 and PIR121/Sra-1/CYFIP/GEX-2. Here, we show that the WAVE1 regulatory protein complex is partly conserved in plants. We have identified Arabidopsis genes encoding homologs of NAP1 (NAPP), PIR121 (PIRP), and HSPC300 (BRK1). T-DNA inactivation of NAPP and PIRP results in distorted trichomes, similar to ARP2/3 complex mutants. The napp-1 mutant is allelic to the distorted mutant gnarled. The actin cytoskeleton in napp-1 and pirp-1 mutants shows orientation defects and increased bundling compared with wild-type plants. The results presented show that activity of the ARP2/3 complex in plants is regulated through an evolutionarily conserved mechanism.
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