ArticleEuropean archives of psychiatry and clinical neuroscience2004
5HT-2C receptor polymorphism in suicide victims. Association studies in German and Slavic populations.
Article in European archives of psychiatry and clinical neuroscience, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Comprehensive view of suicide: A neuro-immune-endocrine approach.World journal of psychiatry · 2025Review
- The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference.International journal of molecular sciences · 2022Review
- Gender differences in the association betweenNeuropsychiatric disease and treatment · 2017Article
- Article
- The neurobiology of suicide - A Review of post-mortem studies.Journal of molecular psychiatry · 2013Review
- 5-HT2C receptor and MAO-A interaction analysis: no association with suicidal behaviour in bipolar patients.European archives of psychiatry and clinical neuroscience · 2008Article
- Stress, genes and the biology of suicidal behavior.The Psychiatric clinics of North America · 2008Review
- Gonadal axis hormones in psychiatric male patients after a suicide attempt.European archives of psychiatry and clinical neuroscience · 2007Article
- Genetics of suicide.Molecular psychiatry · 2006Review
- Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters.European archives of psychiatry and clinical neuroscience · 2005Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sustainable observations suggest that suicidal behaviour by itself may have biological correlates, among which those related to the serotonergic synapse hold the key position. Based on the association of suicide and serotonergic dysfunction, it was proposed that genetic mechanisms affecting suicidal behaviour could be related to the alterations of the genes encoding the elements of 5HT synapse. The present study tested the association of the polymorphism in the serotonin 2C (5HT-2C) receptor coding region (Cys23Ser) with suicide commitment. Study was based on two independent samples, one of German (284 suicide victims versus 297 controls) and other of Slavic/Croatian (118 suicide victims versus 275 controls) ethnicity. No significant differences in allele or genotype frequencies between victims and controls were demonstrated. Results did not provide supporting evidence for the potential involvement of the investigated variants of 5HT-2C receptor in the susceptibility to suicide.
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Registered trials
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