ArticleJournal of neurophysiology2005
Hair-cell versus afferent adaptation in the semicircular canals.
Article in Journal of neurophysiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 48 citations in OpenAlex.
- Adaptation of vestibular signals for self-motion perception.The Journal of physiology · 2011Trial
- Modeling of magnetic vestibular stimulation experienced during high-field clinical MRI.Communications medicine · 2025Article
- Using macular velocity measurements to relate parameters of bone conduction to vestibular compound action potential responses.Scientific reports · 2023Article
- A mathematical model for mechanical activation and compound action potential generation by the utricle in response to sound and vibration.Frontiers in neurology · 2023Article
- Study the biomechanical performance of the membranous semicircular canal based on bionic models.Heliyon · 2022Article
- Article
- Endolymphatic Potential Measured From Developing and Adult Mouse Inner Ear.Frontiers in cellular neuroscience · 2020Article
- Semicircular canal biomechanics in health and disease.Journal of neurophysiology · 2019Review
- Sound abnormally stimulates the vestibular system in canal dehiscence syndrome by generating pathological fluid-mechanical waves.Scientific reports · 2018Article
- Wave Mechanics of the Vestibular Semicircular Canals.Biophysical journal · 2017Article
- A model of signal processing at the isolated hair cell of the frog semicircular canal.Journal of computational neuroscience · 2017Article
- Sensing External and Self-Motion with Hair Cells: A Comparison of the Lateral Line and Vestibular Systems from a Developmental and Evolutionary Perspective.Brain, behavior and evolution · 2017Review
- Electrophysiological Measurements of Peripheral Vestibular Function-A Review of Electrovestibulography.Frontiers in systems neuroscience · 2017Review
- BODIPY-Conjugated Xyloside Primes Fluorescent Glycosaminoglycans in the Inner Ear of Opsanus tau.Journal of the Association for Research in Otolaryngology : JARO · 2016Article
- Spinal corollary discharge modulates motion sensing during vertebrate locomotion.Nature communications · 2015Article
- Hair cell-type dependent expression of basolateral ion channels shapes response dynamics in the frog utricle.Frontiers in cellular neuroscience · 2015Article
- Article
- Voltage-gated Ca2+ channels in accessory lobe neurons of the chick.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- The anatomical and physiological framework for vestibular prostheses.Anatomical record (Hoboken, N.J. : 2007) · 2012Review
- The sense of self-motion, orientation and balance explored by vestibular stimulation.The Journal of physiology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
The time course and extent of adaptation in semicircular canal hair cells was compared to adaptation in primary afferent neurons for physiological stimuli in vivo to study the origins of the neural code transmitted to the brain. The oyster toadfish, Opsanus tau, was used as the experimental model. Afferent firing-rate adaptation followed a double-exponential time course in response to step cupula displacements. The dominant adaptation time constant varied considerably among afferent fibers and spanned six orders of magnitude for the population ( approximately 1 ms to >1,000 s). For sinusoidal stimuli (0.1-20 Hz), the rapidly adapting afferents exhibited a 90 degrees phase lead and frequency-dependent gain, whereas slowly adapting afferents exhibited a flat gain and no phase lead. Hair-cell voltage and current modulations were similar to the slowly adapting afferents and exhibited a relatively flat gain with very little phase lead over the physiological bandwidth and dynamic range tested. Semicircular canal microphonics also showed responses consistent with the slowly adapting subset of afferents and with hair cells. The relatively broad diversity of afferent adaptation time constants and frequency-dependent discharge modulations relative to hair-cell voltage implicate a subsequent site of adaptation that plays a major role in further shaping the temporal characteristics of semicircular canal afferent neural signals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.