ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2004
The effect of water on protein dynamics.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 63 citations in OpenAlex.
- Functions of prolyl hydroxylation in elastin.The Journal of biological chemistry · 2026Article
- Life resists chemistry not conditions.FEMS microbes · 2026Article
- Influence of Salinity on the Extracellular Enzymatic Activities of Marine Pelagic Fungi.Journal of fungi (Basel, Switzerland) · 2024Article
- Release of cell-free enzymes by marine pelagic fungal strains.Frontiers in fungal biology · 2023Article
- Characterization of a novel halotolerant esterase from3 Biotech · 2020Article
- Extremophile Microbial Communities and Enzymes for Bioenergetic Application Based on Multi-Omics Tools.Current genomics · 2020Review
- Characterizing Protein Hydration Dynamics Using Solution NMR Spectroscopy.Methods in enzymology · 2019Article
- Enzymatic turnover of macromolecules generates long-lasting protein-water-coupled motions beyond reaction steady state.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Low-temperature molecular dynamics simulations of horse heart cytochrome c and comparison with inelastic neutron scattering data.European biophysics journal : EBJ · 2013Article
- Halophilic bacteria as a source of novel hydrolytic enzymes.Life (Basel, Switzerland) · 2013Review
- From macromolecules to electrons-grand challenges in theoretical and computational chemistry.Frontiers in chemistry · 2013Article
- Water-protein interactions: the secret of protein dynamics.TheScientificWorldJournal · 2013Article
- Function and biotechnology of extremophilic enzymes in low water activity.Aquatic biosystems · 2012Article
- Mapping the hydration dynamics of ubiquitin.Journal of the American Chemical Society · 2011Article
- Site-resolved measurement of water-protein interactions by solution NMR.Nature structural & molecular biology · 2011Article
- Yield-determining factors in high-solids enzymatic hydrolysis of lignocellulose.Biotechnology for biofuels · 2009Article
- Hemoglobin senses body temperature.European biophysics journal : EBJ · 2009Article
- Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations.The journal of physical chemistry. B · 2008Article
- Molecular processes in biological thermosensation.Journal of biophysics (Hindawi Publishing Corporation : Online) · 2008Article
- Neutron scattering reveals extremely slow cell water in a Dead Sea organism.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neutron diffraction and spectroscopy were applied to describe the hydration and dynamics of a soluble protein and a natural membrane from extreme halophilic Archaea. The quantitative dependence of protein motions on water activity was clearly illustrated, and it was established that a minimum hydration shell is required for the systems to access their functional resilience, i.e. a dynamics state that allows biological activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.