ArticleProceedings. Biological sciences2004
The evolution of non-reciprocal nuclear exchange in mushrooms as a consequence of genomic conflict.
Article in Proceedings. Biological sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Longevity of Fungal Mycelia and Nuclear Quality Checks: a New Hypothesis for the Role of Clamp Connections in Dikaryons.Microbiology and molecular biology reviews : MMBR · 2023Review
- Genome Assembly and Genetic Traits of the Pleuromutilin-ProducerJournal of fungi (Basel, Switzerland) · 2022Article
- Species determination using AI machine-learning algorithms: Hebeloma as a case study.IMA fungus · 2022Article
- Modeling the consequences of the dikaryotic life cycle of mushroom-forming fungi on genomic conflict.eLife · 2022Article
- Cytoplasmic Mixing, Not Nuclear Coexistence, Can Explain Somatic Incompatibility in Basidiomycetes.Microorganisms · 2021Review
- Syncytia in Fungi.Cells · 2020Review
- Nuclear arms races: Experimental evolution for mating success in the mushroom-forming fungus Schizophyllum commune.PloS one · 2018Article
- Unholy marriages and eternal triangles: how competition in the mushroom life cycle can lead to genomic conflict.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Evolutionarily advanced ant farmers rear polyploid fungal crops.Journal of evolutionary biology · 2015Article
- What cost mitochondria? The maintenance of functional mitochondrial DNA within and across generations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- The scope for nuclear selection within Termitomyces fungi associated with fungus-growing termites is limited.BMC evolutionary biology · 2014Article
- A single mating-type locus composed of homeodomain genes promotes nuclear migration and heterokaryosis in the white-rot fungus Phanerochaete chrysosporium.Eukaryotic cell · 2011Article
- Sexual selection in mushroom-forming basidiomycetes.Proceedings. Biological sciences · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterothallic mushrooms accomplish sex by exchanging nuclei without cytoplasm. Hyphal fusions occur between haploid mycelia resulting from germinated spores and subsequent reciprocal nuclear exchange without cytoplasmic mixing. The resulting dikaryon is therefore a cytoplasmic mosaic with uniformly distributed nuclei (two in each cell). Cytoplasmic inheritance is doubly uniparental: both mated monokaryons can potentially transmit their cytoplasm to the sexual spores, but normally only a single type per spore is found. Intracellular competition between mitochondria is thus limited, but at the dikaryon level, the two types of mitochondria compete over transmission. This creates the conditions for genomic conflict: within the dikaryon, a selfish mitochondrial mutant with increased relative transmission can be favoured, but selection between dikaryons will act against such a mitochondrial mutant. Moreover, because nuclear fitness is directly dependent on dikaryon fitness, a reduction in dikaryon fitness directly conflicts with nuclear interests. We propose that genomic conflict explains the frequent occurrence of non-reciprocal nuclear exchange in mushrooms. With non-reciprocal exchange, one monokaryon donates a nucleus and the other accepts it, but not vice versa as in the typical life cycle. We propose a model where non-reciprocal nuclear exchange is primarily driven by mitochondria inducing male sterility and the evolution of nuclear suppressors.
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