ArticleProceedings. Biological sciences2004
Sex as a response to oxidative stress: a twofold increase in cellular reactive oxygen species activates sex genes.
Article in Proceedings. Biological sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Review
- Apomixis: oh, what a tangled web we have!Planta · 2023Review
- A personal cost of cheating can stabilize reproductive altruism during the early evolution of clonal multicellularity.Biology letters · 2022Article
- Trade-off between sex and growth in diatoms: Molecular mechanisms and demographic implications.Science advances · 2022Article
- Novel Approaches for Species Concepts and Delimitation in Polyploids and Hybrids.Plants (Basel, Switzerland) · 2022Review
- Stress conditions promoteeLife · 2022Article
- Mating type specific transcriptomic response to sex inducing pheromone in the pennate diatom Seminavis robusta.The ISME journal · 2021Article
- Whether Gametophytes are Reduced or Unreduced in Angiosperms Might Be Determined Metabolically.Genes · 2020Article
- Article
- Review
- When Unity Is Strength: The Strategies Used byCells · 2019Review
- Many Facets of Dynamic Plasticity in Plants.Cold Spring Harbor perspectives in biology · 2019Review
- Metabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells.The EMBO journal · 2019Article
- A Full-Length Reference Floral Transcriptome ofInternational journal of genomics · 2019Article
- How oxygen gave rise to eukaryotic sex.Proceedings. Biological sciences · 2018Review
- Apomixis frequency under stress conditions in weeping lovegrass (Eragrostis curvula).PloS one · 2017Article
- Volvox: A simple algal model for embryogenesis, morphogenesis and cellular differentiation.Developmental biology · 2016Review
- The evolution of meiotic sex and its alternatives.Proceedings. Biological sciences · 2016Review
- Evolutionary consequences of polyploidy in prokaryotes and the origin of mitosis and meiosis.Biology direct · 2016Article
- Photoperiod Extension Enhances Sexual Megaspore Formation and Triggers Metabolic Reprogramming in Facultative Apomictic Ranunculus auricomus.Frontiers in plant science · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organisms are constantly subjected to factors that can alter the cellular redox balance and result in the formation of a series of highly reactive molecules known as reactive oxygen species (ROS). As ROS can be damaging to biological structures, cells evolved a series of mechanisms (e.g. cell-cycle arrest, programmed cell death) to respond to high levels of ROS (i.e. oxidative stress). Recently, we presented evidence that in a facultatively sexual lineage--the multicellular green alga Volvox carteri--sex is an additional response to increased levels of stress, and probably ROS and DNA damage. Here we show that, in V. carteri, (i) sex is triggered by an approximately twofold increase in the level of cellular ROS (induced either by the natural sex-inducing stress, namely heat, or by blocking the mitochondrial electron transport chain with antimycin A), and (ii) ROS are responsible for the activation of sex genes. As most types of stress result in the overproduction of ROS, we believe that our findings will prove to extend to other facultatively sexual lineages, which could be indicative of the ancestral role of sex as an adaptive response to stress and ROS-induced DNA damage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.