Evidence map›Paper›PMID 15305121›Full record

ReviewNeuroreport2004

The dorsal diencephalic conduction system of zebrafish as a model of vertebrate brain lateralisation.

Miguel L Concha

Open access · greenAbstract readReview
In one paragraph

Review in Neuroreport, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Zebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2009
    Article
  5. The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2009
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Miguel L ConchaPrograma de Morfología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Clasificador 7 Correo 7, Santiago, Chile. mconcha@med.uchile.cl
University of Chile · CL

Funding

Wellcome Trust 068754
6 · The paper itself

Abstract

Lateralisation is an attractive and intriguing feature of the vertebrate CNS studied for decades in the different disciplines of the neurosciences. Due to the complexity of the phenomena and intrinsic limitations of the approaches used to date, it has been difficult to establish useful links between the different, and usually distant, levels of lateralisation e.g. between genetics, morphology, physiology and behaviour. Recently, the dorsal diencephalon of the teleost zebrafish has emerged as a valuable model to begin addressing this issue and as a result unravel the role of vertebrate CNS lateralisation. Zebrafish is a well-established genetic system that allows a 'bottom up' ('gene to behaviour') approach to the study of lateralisation. In fact, it is the single vertebrate system to date in which asymmetric gene expression in the brain has been directly linked to asymmetric morphology. Zebrafish offers several experimental advantages that allow the study of brain lateralisation using a wide range of experimental tools, from study of gene function through in vivo analysis of morphology and physiology to behavioural assessments. Altogether, these features will allow the establishment of operational links between lower (genetics and morphology) and upper (physiology and behaviour) levels of brain lateralisation.

Indexed as

Models, BiologicalAnimalsBehavior, AnimalBrainDiencephalonFunctional LateralityGene Expression Regulation, DevelopmentalModels, AnimalSystems TheoryVertebratesZebrafish

Identifiers

PMID15305121
PMCPMC1350661
OpenAlexW2134843540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.