ArticleAmerican journal of human genetics2004
Attention deficit hyperactivity disorder: fine mapping supports linkage to 5p13, 6q12, 16p13, and 17p11.
Article in American journal of human genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Combined family-based association and linkage analyses in families affected by attention-deficit hyperactivity disorder.Human genetics · 2026Pooled it
- Integrating Forensic Autopsies with Proteomic Profiling for Suicide Risk Assessment: A Comprehensive Review of Literature.Current neuropharmacology · 2025Pooled it
- Association of Serotonin Receptors with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis.Current medical science · 2018Pooled it
- Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2008Pooled it
- A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs.Molecular psychiatry · 2006Trial
- A Systematic Screening of ADHD-Susceptible Variants From 25 Chinese Parents-Offspring Trios.Frontiers in genetics · 2022Article
- Differential Dorsolateral Prefrontal Cortex Proteomic Profiles of Suicide Victims with Mood Disorders.Genes · 2020Article
- A Review of Heterogeneity in Attention Deficit/Hyperactivity Disorder (ADHD).Frontiers in human neuroscience · 2019Review
- A clinical update on tuberous sclerosis complex-associated neuropsychiatric disorders (TAND).American journal of medical genetics. Part C, Seminars in medical genetics · 2018Review
- Analysis of shared homozygosity regions in Saudi siblings with attention deficit hyperactivity disorder.Psychiatric genetics · 2017Article
- Genetic Variations in Attention Deficit Hyperactivity Disorder Subtypes and Treatment Resistant Cases.Psychiatry investigation · 2016Article
- Moving towards causality in attention-deficit hyperactivity disorder: overview of neural and genetic mechanisms.The lancet. Psychiatry · 2016Review
- GDNF gene is associated with tourette syndrome in a family study.Movement disorders : official journal of the Movement Disorder Society · 2015Article
- Abnormal Astrocytosis in the Basal Ganglia Pathway of Git1(-/-) Mice.Molecules and cells · 2015Article
- Genetics in child and adolescent psychiatry: methodological advances and conceptual issues.European child & adolescent psychiatry · 2015Review
- Comorbidity of ADHD and incontinence in children.European child & adolescent psychiatry · 2015Review
- Using Sibling Designs to Understand Neurodevelopmental Disorders: From Genes and Environments to Prevention Programming.BioMed research international · 2015Review
- Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake.Current nutrition reports · 2014Article
- Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment.Genes, brain, and behavior · 2014Article
- The genetics of attention deficit/hyperactivity disorder in adults, a review.Molecular psychiatry · 2012Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
We completed fine mapping of nine positional candidate regions for attention-deficit/hyperactivity disorder (ADHD) in an extended population sample of 308 affected sibling pairs (ASPs), constituting the largest linkage sample of families with ADHD published to date. The candidate chromosomal regions were selected from all three published genomewide scans for ADHD, and fine mapping was done to comprehensively validate these positional candidate regions in our sample. Multipoint maximum LOD score (MLS) analysis yielded significant evidence of linkage on 6q12 (MLS 3.30; empiric P=.024) and 17p11 (MLS 3.63; empiric P=.015), as well as suggestive evidence on 5p13 (MLS 2.55; empiric P=.091). In conjunction with the previously reported significant linkage on the basis of fine mapping 16p13 in the same sample as this report, the analyses presented here indicate that four chromosomal regions--5p13, 6q12, 16p13, and 17p11--are likely to harbor susceptibility genes for ADHD. The refinement of linkage within each of these regions lays the foundation for subsequent investigations using association methods to detect risk genes of moderate effect size.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.