Evidence map›Paper›PMID 15297555›Full record

ArticleJournal of clinical microbiology2004

Evaluation of a new automated, standardized generic nucleic acid extraction method (total nucleic acid isolation kit) used in combination with cytomegalovirus DNA quantification by COBAS AMPLICOR CMV MONITOR.

Barbara Christine Gärtner, Johannes Michael Fischinger, Anke Litwicki, Klaus Roemer, Nikolaus Mueller-Lantzsch

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barbara Christine GärtnerInstitute of Virology, University of the Saarland, Homburg/Saar, Haus 47, D-66421 Homburg/Saar, Germany. vibgae@uniklinik-saarland.de
Johannes Michael Fischinger
Anke Litwicki
Klaus Roemer
Nikolaus Mueller-Lantzsch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new generic Total Nucleic Acid Isolation kit improved the detection limit of a cytomegalovirus (CMV) PCR from 400 to 200 copies/ml. Sensitivity and specificity in 30 CMV-positive and 100 negative samples were 100%. Analytical performance was excellent. The kit provides a reliable, standardized, and time-saving tool for DNA extraction.

Indexed as

AutomationCells, CulturedCytomegalovirusCytomegalovirus InfectionsDNA, ViralHumansPolymerase Chain ReactionPostoperative ComplicationsReagent Kits, DiagnosticRNA, ViralSensitivity and SpecificityTransplantationDNA, ViralReagent Kits, DiagnosticRNA, Viral

Identifiers

PMID15297555
PMCPMC497653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.