ArticleSports medicine (Auckland, N.Z.)2004
Exercise immunology: the current state of man and mouse.
Article in Sports medicine (Auckland, N.Z.), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 63 citations in OpenAlex.
- The influence of hydration status during prolonged endurance exercise on salivary antimicrobial proteins.European journal of applied physiology · 2015Trial
- (Ultra-)inflammation or adaptation? Comparison of different ultramarathon distances and their effect on the immune system.Frontiers in immunology · 2026Article
- Increasing prevalence and influencing factors of childhood asthma: a cross-sectional study in Shanghai, China.World journal of pediatrics : WJP · 2021Article
- Positive transcriptional response on inflammation and joint remodelling influenced by physical exercise in proteoglycan-induced arthritis: An animal study.Bone & joint research · 2020Article
- Immunomodulation From Moderate Exercise Promotes Control of Experimental Cutaneous Leishmaniasis.Frontiers in cellular and infection microbiology · 2019Article
- Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice.Journal of innate immunity · 2018Article
- Moderate Exercise Enhances the Production of Interferon-γ and Interleukin-12 in Peripheral Blood Mononuclear Cells.Immune network · 2017Article
- Effect of Physical Exercise on the Febrigenic Signaling is Modulated by Preoptic Hydrogen Sulfide Production.PloS one · 2017Article
- Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes.Biomedical reports · 2016Article
- Effect of Moderate Exercise on Serum Interferon-Gamma and Interleukin-17 Levels in the Morphine Withdrawal Period.International journal of high risk behaviors & addiction · 2016Article
- Comparison of Effect of One Course of Intense Exercise (Wingate test) on Serum Levels of Interleukin-17 in Different Groups of Athletes.Asian journal of sports medicine · 2014Article
- Moderate physical exercise protects myenteric metabolically more active neurons in mice infected with Trypanosoma cruzi.Digestive diseases and sciences · 2014Article
- Amino acid supplementation and impact on immune function in the context of exercise.Journal of the International Society of Sports Nutrition · 2014Article
- Cytokine production by monocytes, neutrophils, and dendritic cells is hampered by long-term intensive training in elite swimmers.European journal of applied physiology · 2012Article
- Immunomodulatory effects of aerobic training in obesity.Mediators of inflammation · 2011Article
- Recovery after an Ironman triathlon: sustained inflammatory responses and muscular stress.European journal of applied physiology · 2008Article
- Muscular damage and intravascular haemolysis during an 18 hour subterranean exploration in a cave of 700 m depth.British journal of sports medicine · 2006Article
- Exercising in environmental extremes : a greater threat to immune function?Sports medicine (Auckland, N.Z.) · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms governing the body's response to physical exercise have been investigated from various perspectives including metabolism, nutrition, age and sex. Increased attention to the immune system during recent decades is reflected by a rapidly growing number of publications in the field. This article highlights the most recent findings and only briefly summarises more basic concepts already reviewed by others. Topics include Th1/Th2 cytokine balance, inoculation time, age and immune compensation. Some less investigated areas are discussed including studies in children, the environment and dendritic cells. Because physical exercise enhances some aspects and suppresses other aspects of immunity, the biological significance of alterations in the immune system are unknown. So far, no link between immunological alterations and infection rate has been established and infection after strenuous physical exercise is equally likely to be the result of exercising with an already established rather than a new infection. If there is an increased risk for infections with increased exercise duration and intensity, why do overtrained athletes not display the greatest risk for upper respiratory tract infections? Increased knowledge on immune system modulations with physical exercise is relevant both from a public health and elite athlete's point of view.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.