ArticleJournal of medical ethics2004
Nicotine conjugate vaccine: is there a right to a smoking future?
Article in Journal of medical ethics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nicotine vaccines for smoking cessation.The Cochrane database of systematic reviews · 2012Pooled it
- Effect of a nicotine vaccine on nicotine binding to β2*-nicotinic acetylcholine receptors in vivo in human tobacco smokers.The American journal of psychiatry · 2013Trial
- Nicotine replacement therapy: A friend or foe.Journal of family medicine and primary care · 2020Review
- Ethical Implications in Vaccine Pharmacotherapy for Treatment and Prevention of Drug of Abuse Dependence.Journal of bioethical inquiry · 2018Article
- Foetal surgery and using in utero therapies to reduce the degree of disability after birth. Could it be morally defensible or even morally required?Medicine, health care, and philosophy · 2017Article
- Lifestyle Vaccines and Public Health: Exploring Policy Options for a Vaccine to Stop Smoking.Public health ethics · 2016Article
- Enhancing Children against Unhealthy Behaviors-An Ethical and Policy Assessment of Using a Nicotine Vaccine.Public health ethics · 2013Article
- Nicotine vaccines to treat tobacco dependence.Human vaccines & immunotherapeutics · 2013Review
- Immune to addiction: the ethical dimensions of vaccines against substance abuse.Nature immunology · 2012Article
- Review
- Targeting nicotine addiction: the possibility of a therapeutic vaccine.Drug design, development and therapy · 2011Review
- Novel pharmacological approaches for treating tobacco dependence and withdrawal: current status.Drugs · 2008Review
- A research agenda for assessing the potential contribution of genomic medicine to tobacco control.Tobacco control · 2007Article
- Regarding articles on nicotine and cocaine dependence.Psychiatry (Edgmont (Pa. : Township)) · 2006Article
- Further ethical and social issues in using a cocaine vaccine: response to Hall and Carter.Journal of medical ethics · 2004Article
- Preventing sin: the ethics of vaccines against smoking.The Hastings Center reportArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tobacco consumption is believed to be one of the world's greatest preventable health problems. According to the World Health Organisation, 1.1 billion people worldwide are addicted to nicotine with tobacco causing an estimated four million premature deaths every year. The development of a nicotine conjugate vaccine suggests that immunisation may hold promise as a future therapeutic and preventive strategy for tobacco smoking and nicotine addiction. Allowing parents to immunise their children against smoking could be an infringement of children's right to an open future, however, and is not ethically unproblematic
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.