ArticlePlant molecular biology2004
Members of a new group of chitinase-like genes are expressed preferentially in cotton cells with secondary walls.
Article in Plant molecular biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 80 citations in OpenAlex.
- Comprehensive insights into the development of arabidopsis trichomes by single-nucleus RNA-seq.BMC plant biology · 2026Article
- Identification of Stable Meta-QTLs and Candidate Genes Underlying Fiber Quality and Agronomic Traits in Cotton.Plants (Basel, Switzerland) · 2025Article
- Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development.Journal of advanced research · 2024Article
- Genome-Wide Identification of a Maize Chitinase Gene Family and the Induction of Its Expression byGenes · 2024Article
- An Unexpected Regulatory Sequence from Rho-Related GTPase6 Confers Fiber-Specific Expression in Upland Cotton.International journal of molecular sciences · 2022Article
- Sulfur-Induced Resistance againstInternational journal of molecular sciences · 2021Article
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- Genome-wide identification and characterization of TALE superfamily genes in cotton reveals their functions in regulating secondary cell wall biosynthesis.BMC plant biology · 2019Article
- The cell biology of secondary cell wall biosynthesis.Annals of botany · 2018Review
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- A Cotton Annexin Affects Fiber Elongation and Secondary Cell Wall Biosynthesis Associated with Ca2+ Influx, ROS Homeostasis, and Actin Filament Reorganization.Plant physiology · 2016Article
- GbEXPATR, a species-specific expansin, enhances cotton fibre elongation through cell wall restructuring.Plant biotechnology journal · 2016Article
- Cotton KNL1, encoding a class II KNOX transcription factor, is involved in regulation of fibre development.Journal of experimental botany · 2014Article
- Down-regulating annexin gene GhAnn2 inhibits cotton fiber elongation and decreases Ca2+ influx at the cell apex.Plant molecular biology · 2014Article
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- Isolation, characterization and mapping of genes differentially expressed during fibre development between Gossypium hirsutum and G. barbadense by cDNA-SRAP.Journal of genetics · 2013Article
- Identification and expression analysis of chitinase genes related to biotic stress resistance in Brassica.Molecular biology reports · 2012Article
- Chitinase-like1/pom-pom1 and its homolog CTL2 are glucan-interacting proteins important for cellulose biosynthesis in Arabidopsis.The Plant cell · 2012Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two homologous cotton (Gossypium hirsutum L.) genes, GhCTL1 and GhCTL2, encode members of a new group of chitinase-like proteins (called the GhCTL group) that includes other proteins from two cotton species, Arabidopsis, rice, and pea. Members of the GhCTL group are assigned to family GH19 glycoside hydrolases along with numerous authentic chitinases (http://afmb.cnrs-mrs.fr/CAZY/index.html), but the proteins have novel consensus sequences in two regions that are essential for chitinase activity and that were previously thought to be conserved. Maximum parsimony phylogenetic analyses, as well as Neighbor-Joining distance analyses, of numerous chitinases confirmed that the GhCTL group is distinct. A molecular model of GhCTL2 (based on the three-dimensional structure of a barley chitinase) had changes in the catalytic site that are likely to abolish catalytic activity while retaining potential to bind chitin oligosaccharides. RNA blot analysis showed that members of the GhCTL group had preferential expression during secondary wall deposition in cotton lint fiber. Cotton transformed with a fusion of the GhCTL2 promoter to the beta -d-glucuronidase gene showed preferential reporter gene activity in numerous cells during secondary wall deposition. Together with evidence from other researchers that mutants in an Arabidopsis gene within the GhCTL group are cellulose-deficient with phenotypes indicative of altered primary cell walls, these data suggest that members of the GhCTL group of chitinase-like proteins are essential for cellulose synthesis in primary and secondary cell walls. However, the mechanism by which they act is more likely to involve binding of chitin oligosaccharides than catalysis.
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Registered trials
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