Evidence map›Paper›PMID 15280423›Full record

ArticleThe Journal of experimental medicine2004

Suppressor T cells in human diseases.

Clare Baecher-Allan, David A Hafler

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of experimental medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 169 citations in OpenAlex.

  1. Article
  2. The Role of MicroRNAs in Regulatory T Cells.Journal of immunology research · 2020
    Review
  3. Interleukin-7 and Immunosenescence.Journal of immunology research · 2017
    Review
  4. Article
  5. Article
  6. Translating Treg Therapy in Humanized Mice.Frontiers in immunology · 2015
    Review
  7. Influence of human myasthenia gravis thymus on the differentiation of human cord blood stem cells in SCID mice.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2014
    Article
  8. Midkine and multiple sclerosis.British journal of pharmacology · 2014
    Review
  9. Interleukin-7 mediates selective expansion of tumor-redirected cytotoxic T lymphocytes (CTLs) without enhancement of regulatory T-cell inhibition.Clinical cancer research : an official journal of the American Association for Cancer Research · 2014
    Article
  10. Lymphocyte subsets in pediatric migraine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013
    Article
  11. Article
  12. Article
  13. RNA plasticity and selectivity applicable to therapeutics and novel biosensor development.Genes to cells : devoted to molecular & cellular mechanisms · 2012
    Review
  14. Changes in chemokine receptor expression of regulatory T cells after ex vivo culture.Journal of immunotherapy (Hagerstown, Md. : 1997) · 2012
    Article
  15. Article
  16. In vitro Treg suppression assays.Methods in molecular biology (Clifton, N.J.) · 2011
    Article
  17. Article
  18. An imbalance of esophageal effector and regulatory T cell subsets in experimental eosinophilic esophagitis in mice.American journal of physiology. Gastrointestinal and liver physiology · 2009
    Article
  19. Article
  20. A role for CXCL13 (BCA-1) in pregnancy and intra-amniotic infection/inflammation.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2008
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Clare Baecher-AllanHarvard Medical School, 77 Ave. Louis Pasteur, Boston, MA 02115, USA. callan@rics.bwh.harvard.edu
David A Hafler
Brigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although central and peripheral tolerance are important for the regulation of human immune responses to self- and microbial antigens, an important role of suppressor CD4(+) CD25(+) T cells is suggested from the recent investigations of human autoimmune diseases and HIV. These new data provide increasing evidence that altered function of CD4(+) CD25(+) T cells may be an important factor in a wide range of human inflammatory and infectious diseases.

Indexed as

Arthritis, RheumatoidCD4 AntigensHIV InfectionsHumansMultiple SclerosisReceptors, Interleukin-2T-Lymphocytes, RegulatoryCD4 AntigensReceptors, Interleukin-2

Identifiers

PMID15280423
PMCPMC2211973
OpenAlexW2123677383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.