Trial reportInternational journal of cardiac imaging1992
Measuring progression and regression of coronary atherosclerosis in clinical trials: problems and progress.
Trial report in International journal of cardiac imaging, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 36 citations in OpenAlex.
- Accuracy and precision of quantitative arteriography in the evaluation of coronary artery disease after coronary bypass surgery. A validation study.International journal of cardiac imaging · 1994Trial
- Angiographically borderline left main coronary artery lesions: correlation of transthoracic doppler echocardiography and intravascular ultrasound: a pilot study.Cardiovascular ultrasound · 2011Article
- Evaluation of coronary atheroma by 64-slice multidetector computed tomography: Comparison with intravascular ultrasound and angiography.The Canadian journal of cardiology · 2009Article
- Validation of coronary artery saphenous vein bypass graft diameter measurements using quantitative angiography.International journal of cardiac imaging · 1996Article
- Automated extraction, labelling and analysis of the coronary vasculature from arteriograms.International journal of cardiac imaging · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interventions that may influence the evolution of coronary atherosclerosis can be evaluated more rapidly and efficiently in clinical trials with angiographic endpoints as opposed to using coronary events as endpoints. Quantitative coronary arteriography provides precise and reproducible measurements of coronary artery dimensions for this purpose. The variability of 2 quantitative systems was assessed in 54 lesions under 4 different conditions: same film, same frame; same film, same view; different frame; same view from different films obtained within one month; and same view from different films obtained one to 6 months apart. With the Cardiovascular Angiographic Analysis System (CAAS), variability of repeat measurement of minimum diameter, expressed as 1 standard deviation of the mean, increased from 0.088 mm (same frame) to 0.197 mm (films 1 to 6 months apart) as conditions decreased from optimal to those encountered in clinical studies. With the Cardiovascular Measurement System (CMS), 1 standard deviation for repeat measurements of minimum diameter increased from 0.087 mm (same frame to 0.240 mm (films one to 6 months apart). The differences between the two systems for measurements of minimum diameter were not statistically significant and CMS tracked the arterial edge more meticulously than did CAAS. A change in minimum diameter greater than or equal to 0.4 mm for CAAS or greater than or equal to 0.48 mm for CMS is more than 2 standard deviations of the mid-term variability and therefore represents a true change, either progression or regression, with greater than 95% probability. Quantitative coronary arteriography is an essential tool in clinical trials to assess the effect of an intervention upon the evolution of coronary atherosclerosis.(ABSTRACT TRUNCATED AT 250 WORDS)
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.