Evidence map›Paper›PMID 15273149›Full record

ArticleAntimicrobial agents and chemotherapy2004

High prevalence of the ermB gene among erythromycin-resistant streptococcus pneumoniae isolates in Germany during the winter of 2000-2001 and in vitro activity of telithromycin.

Michael Kresken, Beate Henrichfreise, Simone Bagel, Johannes Brauers, Bernd Wiedemann

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael KreskenAntiinfectives Intelligence GmbH, 53121 Bonn, Germany. michael.kresken@antiinfectives-intelligence.de
Beate Henrichfreise
Simone Bagel
Johannes Brauers
Bernd Wiedemann
Federal Office for Information Security · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of 595 isolates of Streptococcus pneumoniae from outpatients with respiratory tract infections, collected from 17 microbiology laboratories, 14.1% were resistant to erythromycin. Eighty-three erythromycin-resistant isolates were genetically analyzed, 83.1% of which harbored the ermB gene. Only four isolates (4.8%) harbored the mefA gene. Telithromycin exhibited potent activity against all isolates.

Indexed as

KetolidesAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldErythromycinGenotypeGermanyMacrolidesMembrane ProteinsMethyltransferasesPneumococcal InfectionsReverse Transcriptase Polymerase Chain ReactionStreptococcus pneumoniaeAnti-Bacterial AgentsBacterial ProteinsErmA protein, BacteriaErythromycinKetolidesMacrolidesMefA protein, StreptococcusMembrane ProteinsMethyltransferasestelithromycin

Identifiers

PMID15273149
PMCPMC478534
OpenAlexW2134910317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.