Evidence map›Paper›PMID 15273140›Full record

ArticleAntimicrobial agents and chemotherapy2004

Temporin A soaking in combination with intraperitoneal linezolid prevents vascular graft infection in a subcutaneous rat pouch model of infection with Staphylococcus epidermidis with intermediate resistance to glycopeptides.

Andrea Giacometti, Oscar Cirioni, Roberto Ghiselli, Fiorenza Orlando, Giuseppina D'Amato, Wojciech Kamysz, Federico Mocchegiani, Valerio Sisti, Carmela Silvestri, Jerzy Łukasiak and 3 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Temporins: Multifunctional Peptides from Frog Skin.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Andrea GiacomettiInstitute of Infectious Diseases and Public Health, Università Politecnica delle Marche, Ancona, Italy. anconacmi@interfree.it
Oscar Cirioni
Roberto Ghiselli
Fiorenza Orlando
Giuseppina D'Amato
Wojciech Kamysz
Federico Mocchegiani
Valerio Sisti
Carmela Silvestri
Jerzy Łukasiak
Marco Rocchi
Vittorio Saba
Giorgio Scalise
Marche Polytechnic University · ITGdańsk Medical University · PLUniversity of Urbino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of linezolid and temporin A in the prevention of prosthetic graft infection due to methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides was investigated in a subcutaneous rat pouch model. Linezolid and temporin A, alone or combined, greatly reduced the bacterial numbers compared to the effect with control drugs.

Indexed as

Blood Vessel ProsthesisStaphylococcus epidermidisAcetamidesAnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesColony Count, MicrobialDrug Resistance, BacterialDrug SynergismGlycopeptidesLinezolidMaleMicrobial Sensitivity TestsOxazolidinonesPharmaceutical SolutionsPolyethylene TerephthalatesAcetamidesAnti-Infective AgentsAntimicrobial Cationic PeptidesGlycopeptidesLinezolidOxazolidinonesPharmaceutical SolutionsPolyethylene TerephthalatesProteinstemporin

Identifiers

PMID15273140
PMCPMC478507
OpenAlexW2106278025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.