Evidence map›Paper›PMID 15273138›Full record

ArticleAntimicrobial agents and chemotherapy2004

Effect of granulocyte colony-stimulating factor combination therapy on efficacy of posaconazole (SCH56592) in an inhalation model of murine pulmonary aspergillosis.

Andriani C Patera, Frederick Menzel, Craig Jackson, Joan K Brieland, Judy Halpern, Roberta Hare, Anthony Cacciapuoti, David Loebenberg

Open access · greenAbstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andriani C PateraSchering-Plough Research Institute, Kenilworth, New Jersey 07033, USA. andriani.patera@spcorp.com
Frederick Menzel
Craig Jackson
Joan K Brieland
Judy Halpern
Roberta Hare
Anthony Cacciapuoti
David Loebenberg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using an inhalation model of pulmonary aspergillosis, we observed modest differences in the survival rates of mice treated with granulocyte colony-stimulating factor (G-CSF) and posaconazole (POS) and those treated with POS alone. This finding is in contrast to a previous report that suggested that G-CSF had a significant antagonistic effect on the antifungal activity of POS.

Indexed as

AnimalsAntifungal AgentsAspergillosis, Allergic BronchopulmonaryDrug Therapy, CombinationGranulocyte Colony-Stimulating FactorLungMaleMiceSurvival AnalysisTriazolesAntifungal AgentsGranulocyte Colony-Stimulating FactorposaconazoleTriazoles

Identifiers

PMID15273138
PMCPMC478512
OpenAlexW2139938432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.