Evidence map›Paper›PMID 15271961›Full record

ArticleInfection and immunity2004

Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.

Helton da Costa Santiago, Carolina Ferreira Oliveira, Luciana Santiago, Fernanda Oliveira Ferraz, Daniele da Glória de Souza, Luiz Antônio Rodrigues de-Freitas, Luís Carlos Crocco Afonso, Mauro Martins Teixeira, Ricardo Tostes Gazzinelli, Leda Quercia Vieira

Abstract read
In one paragraph

Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Pathogens (Basel, Switzerland) · 2021
    Article
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  13. Article
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  15. Article
  16. Review
  17. Article
  18. Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis.Journal of immunology (Baltimore, Md. : 1950) · 2010
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Helton da Costa SantiagoDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Brazil.
Carolina Ferreira Oliveira
Luciana Santiago
Fernanda Oliveira Ferraz
Daniele da Glória de Souza
Luiz Antônio Rodrigues de-Freitas
Luís Carlos Crocco Afonso
Mauro Martins Teixeira
Ricardo Tostes Gazzinelli
Leda Quercia Vieira

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.

Indexed as

Leishmania majorAnimalsChemokine CCL5Leishmaniasis, CutaneousMiceMice, Inbred BALB CMice, Inbred C57BLChemokine CCL5

Identifiers

PMID15271961
PMCPMC470676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.