ReviewImmunology2004
Divide and conquer: the importance of cell division in regulating B-cell responses.
Review in Immunology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed.
- Isotype-specific antibody secreting plasma cells harbor epigenetic and transcription factor architectures defining distinct cell lineages.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- IFNγ-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate.bioRxiv : the preprint server for biology · 2026Article
- Notch2 signaling instructs viral and bacterial TLR responsiveness in B cells.bioRxiv : the preprint server for biology · 2025Article
- G9a controls plasma cell differentiation through FOXO1 and ETS1 binding site regulatory networks.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Majority of human circulating IgG plasmablasts stop blasting in a cell-free pro-survival culture.Scientific reports · 2024Article
- Age-associated changes in innate and adaptive immunity: role of the gut microbiota.Frontiers in immunology · 2024Review
- Hallmarks of CD8Nature immunology · 2023Article
- Epigenetic gene regulation in plasma cells.Immunological reviews · 2021Review
- Know your enemy or find your friend?-Induction of IgA at mucosal surfaces.Immunological reviews · 2021Review
- Article
- A Posttranscriptional Pathway of CD40 Ligand mRNA Stability Is Required for the Development of an Optimal Humoral Immune Response.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Article
- Roadmap to a plasma cell: Epigenetic and transcriptional cues that guide B cell differentiation.Immunological reviews · 2021Review
- Antibody-secreting cell destiny emerges during the initial stages of B-cell activation.Nature communications · 2020Article
- B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells.Frontiers in immunology · 2020Article
- What Will B Will B: Identifying Molecular Determinants of Diverse B-Cell Fate Decisions Through Systems Biology.Frontiers in cell and developmental biology · 2020Review
- Interleukin (IL)-21 Promotes the Differentiation of IgA-Producing Plasma Cells in Porcine Peyer's Patches via the JAK-STAT Signaling Pathway.Frontiers in immunology · 2020Article
- Eosinophils Affect Antibody Isotype Switching and May Partially Contribute to Early Vaccine-Induced Immunity against Coxiella burnetii.Infection and immunity · 2019Article
- Mutations in topoisomerase IIβ result in a B cell immunodeficiency.Nature communications · 2019Article
- Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses.Nature communications · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proliferation is an essential characteristic of clonal selection and is required for the expansion of antigen reactive clones leading to the development of antibody of different isotypes and memory cells. New data for mouse and human B cells point to an important role for division in regulating isotype class and in optimizing development of protective immunity by the regulated entry of cells to the plasma cell lineage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.