Evidence map›Paper›PMID 15269075›Full record

ReviewArchives of disease in childhood2004

Should recombinant human growth hormone therapy be used in short small for gestational age children?

L B Johnston, M O Savage

Abstract readReview
In one paragraph

Review in Archives of disease in childhood, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

L B JohnstonPaediatric Endocrine Section, Department of Endocrinology, William Harvey Research Institute, Barts and the London Queen Mary School of Medicine, London, UK. l.b.Johnston@qmul.ac.uk
M O Savage

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short small for gestational age (SGA) children represent 20% of all children with short stature and therefore constitute a significant portion of the caseload in a growth clinic. The recent approval of recombinant human growth hormone (GH) for the treatment of short stature in SGA children by the European Union's Committee on Proprietary Medicinal Products offers a new licensed therapeutic option. This article examines the role of GH therapy in short SGA children with particular reference to selection of patients, effectiveness, safety, and its potential metabolic implications.

Indexed as

Body CompositionBody HeightHuman Growth HormoneHumansInfantInfant, NewbornInfant, Small for Gestational AgeInsulin-Like Growth Factor IRecombinant ProteinsRisk FactorsTreatment OutcomeHuman Growth HormoneInsulin-Like Growth Factor IRecombinant Proteins

Identifiers

PMID15269075
PMCPMC1720030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.