Evidence map›Paper›PMID 15266437›Full record

SynthesisThe Cochrane database of systematic reviews2004

Topical umbilical cord care at birth.

J Zupan, P Garner, A A A Omari

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 7 pooled it
25.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 7 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Umbilical cord cleansing with chlorhexidine in neonates: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2016
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Umbilical cord antiseptics for preventing sepsis and death among newborns.The Cochrane database of systematic reviews · 2013
    Pooled it
  5. Pooled it
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  7. Topical umbilical cord care at birth.The Cochrane database of systematic reviews · 2004
    Pooled it
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  19. [Guidelines for neonatal skin management in the neonatal intensive care unit (2021)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

J ZupanDepartment of Reproductive Health, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland.
P Garner
A A A Omari
Liverpool School of Tropical Medicine · GBWorld Health Organization · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUmbilical cord infection caused many neonatal deaths before aseptic techniques were used.

objectivesTo assess the effects of topical cord care in preventing cord infection, illness and death. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register (September 2003) and the Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 2, 2003). We also contacted experts in the field. SELECTION CRITERIA: Randomized and quasi-randomized trials of topical cord care compared with no topical care, and comparisons between different forms of care. DATA COLLECTION AND ANALYSIS: Two reviewers assessed trial quality and extracted data. MAIN

resultsTwenty-one studies (8959 participants) were included, the majority of which were from high-income countries. No systemic infections or deaths were observed in any of the studies reviewed. No difference was demonstrated between cords treated with antiseptics compared with dry cord care or placebo. There was a trend to reduced colonization with antibiotics compared to topical antiseptics and no treatment. Antiseptics prolonged the time to cord separation. Use of antiseptics was associated with a reduction in maternal concern about the cord. REVIEWERS'

conclusionsGood trials in low-income settings are warranted. In high-income settings, there is limited research which has not shown an advantage of antibiotics or antiseptics over simply keeping the cord clean. Quality of evidence is low.

Indexed as

Delivery, ObstetricUmbilical CordAnti-Bacterial AgentsAnti-Infective Agents, LocalHumansInfant, NewbornSepsisAnti-Bacterial AgentsAnti-Infective Agents, Local

Identifiers

PMID15266437
PMCPMC6457922
OpenAlexW2156369189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.